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Infed Generic Name & Formulations
Legal Class
Rx
General Description
Iron (as dextran complex) 50mg/mL; soln for IV or IM inj.
Pharmacological Class
Hematinic.
How Supplied
Vials (2mL)—10
Manufacturer
Generic Availability
NO
Infed Indications
Indications
Iron deficiency where oral therapy is intolerable or unsatisfactory response.
Infed Dosage and Administration
Adults and Children
<4mos: not recommended. Give by IV or deep IM inj into upper outer quadrant of buttock only. Administer 0.5mL test dose first; if no signs/symptoms of anaphylactic-type reactions, may give full therapeutic dose. ≥4mos: Iron deficiency anemia: determine total dose based on hemoglobin and body weight (see full labeling). Iron replacement for blood loss: Replacement iron (in mg) = blood loss (in mL) × hematocrit. See full labeling.
Infed Contraindications
Not Applicable
Infed Boxed Warnings
Boxed Warning
Risk for anaphylactic-type reactions.
Infed Warnings/Precautions
Warnings/Precautions
Monitor for anaphylactic-type reactions, esp. in patients with history of drug allergies, asthma; have epinephrine available. Avoid large IV doses; higher incidence of adverse events. Severe hepatic impairment. Avoid during acute phase of infectious kidney disease. Dialysis. Cardiovascular disease. Rheumatoid arthritis. Iron overload. Neonates. Pregnancy. Nursing mothers.
Infed Pharmacokinetics
See Literature
Infed Interactions
Interactions
Concomitant ACE inhibitors may increase the risk for anaphylactic-type reactions. May falsely elevate serum bilirubin or decrease serum calcium levels.
Infed Adverse Reactions
Adverse Reactions
Nausea, vomiting, chest pain, backache, hypersensitivity, dyspnea, hypotension, pruritus, flushing, dizziness; anaphylactic reactions (may be fatal; even if test dose was tolerated), cardiovascular events, inj site reactions, others; possible sepsis in neonates.
Infed Clinical Trials
See Literature
Infed Note
Not Applicable
Infed Patient Counseling
See Literature
