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Auryxia Generic Name & Formulations
Legal Class
Rx
General Description
Ferric iron 210mg (equivalent to 1g ferric citrate); tabs.
Pharmacological Class
Hematinic.
How Supplied
Tabs—200
Manufacturer
Generic Availability
NO
Auryxia Indications
Indications
Iron deficiency anemia in adults with chronic kidney disease not on dialysis.
Auryxia Dosage and Administration
Adult
Swallow whole. Take with meals. Initially 1 tab three times daily; titrate as needed to achieve hemoglobin target levels; max 12 tabs/day.
Children
Not established.
Auryxia Contraindications
Contraindications
Iron overload syndromes (eg, hemochromatosis).
Auryxia Boxed Warnings
Not Applicable
Auryxia Warnings/Precautions
Warnings/Precautions
Monitor serum phosphorus. Assess iron parameters (eg, serum ferritin, TSAT) prior to initiation and monitor during therapy. Accidental iron overdose (esp. in children <6yrs); may be fatal. Pregnancy. Nursing mothers.
Auryxia Pharmacokinetics
See Literature
Auryxia Interactions
Interactions
Concomitant IV iron; may require dose reduction or discontinuation of IV therapy. Give doxycycline at least 1hr before Auryxia. Give ciprofloxacin at least 2hrs before or after Auryxia. Concomitant drugs with narrow therapeutic range; consider monitoring.
Auryxia Adverse Reactions
Adverse Reactions
Diarrhea, discolored feces, constipation, nausea, vomiting, cough, abdominal pain, hyperkalemia; iron overload.
Auryxia Clinical Trials
See Literature
Auryxia Note
Not Applicable
Auryxia Patient Counseling
See Literature
Auryxia Generic Name & Formulations
Legal Class
Rx
General Description
Ferric iron 210mg (equivalent to 1g ferric citrate); tabs.
Pharmacological Class
Phosphate binder.
How Supplied
Tabs—200
Manufacturer
Generic Availability
NO
Auryxia Indications
Indications
To control serum phosphorus levels in patients with chronic kidney disease on dialysis.
Auryxia Dosage and Administration
Adult
Swallow whole. Take with meals. Initially 2 tabs three times daily; titrate in decrements or increments of 1–2 tabs daily as needed at 1-week or longer intervals to maintain target levels; max 12 tabs/day.
Children
Not established.
Auryxia Contraindications
Contraindications
Iron overload syndromes (eg, hemochromatosis).
Auryxia Boxed Warnings
Not Applicable
Auryxia Warnings/Precautions
Warnings/Precautions
Monitor serum phosphorus. Assess iron parameters (eg, serum ferritin, TSAT) prior to initiation and monitor during therapy. Accidental iron overdose (esp. in children <6yrs); may be fatal. Pregnancy. Nursing mothers.
Auryxia Pharmacokinetics
See Literature
Auryxia Interactions
Interactions
Concomitant IV iron; may require dose reduction or discontinuation of IV therapy. Give doxycycline at least 1hr before Auryxia. Give ciprofloxacin at least 2hrs before or after Auryxia. Concomitant drugs with narrow therapeutic range; consider monitoring.
Auryxia Adverse Reactions
Adverse Reactions
Diarrhea, discolored feces, constipation, nausea, vomiting, cough, abdominal pain, hyperkalemia; iron overload.
Auryxia Clinical Trials
See Literature
Auryxia Note
Not Applicable
Auryxia Patient Counseling
See Literature
