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Tigan Injection Generic Name & Formulations
Legal Class
Rx
General Description
Trimethobenzamide HCl 100mg/mL; for IM inj.
Pharmacological Class
Antiemetic.
See Also
How Supplied
Caps—contact supplier; Single-use vials (2mL)—25; Multi-dose vial (20mL)—1
Manufacturer
Tigan Injection Indications
Indications
Treatment of post-op or gastroenteritis-associated nausea and vomiting.
Tigan Injection Dosage and Administration
Adult
Use lowest effective dose. 200mg IM 3–4 times daily.
Children
Not recommended.
Tigan Injection Contraindications
Contraindications
Injection (children).
Tigan Injection Boxed Warnings
Not Applicable
Tigan Injection Warnings/Precautions
Warnings/Precautions
Acute dystonic reactions. Extrapyramidal symptoms. May mask other serious disorders (eg, encephalopathy, metabolic imbalance). Children (Reye's syndrome). Monitor for hepatic impairment; discontinue if occurs. Renal impairment. Elderly. Pregnancy. Nursing mothers.
Tigan Injection Pharmacokinetics
See Literature
Tigan Injection Interactions
Interactions
Potentiated by alcohol (avoid), other CNS depressants (eg, sedatives, hypnotics, opiates, anxiolytics, antipsychotics, anticholinergics); monitor.
Tigan Injection Adverse Reactions
Adverse Reactions
Parkinson-like symptoms, drowsiness, blood dyscrasias, blurred vision, coma, seizures, depression, diarrhea, disorientation, dizziness, jaundice, hypotension (inj), headache, muscle cramps, opisthotonos; hepatotoxicity, hypersensitivity reactions.
Tigan Injection Clinical Trials
See Literature
Tigan Injection Note
Not Applicable
Tigan Injection Patient Counseling
See Literature
