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Sancuso Generic Name & Formulations
Legal Class
Rx
General Description
Granisetron 3.1mg/24hrs; transdermal delivery system (patch).
Pharmacological Class
5-HT3 receptor antagonist.
How Supplied
Patch—1
Manufacturer
Sancuso Indications
Indications
Prevention of nausea and vomiting in patients receiving moderately and/or highly emetogenic chemotherapy regimens of up to 5 consecutive days duration.
Sancuso Dosage and Administration
Adult
≥18yrs: apply one patch to clean, dry, intact healthy skin on upper outer arm 24 to 48 hours before chemotherapy; remove at least 24 hours after chemotherapy is completed. May wear patch for up to 7 days. Do not cut patch.
Children
<18yrs: not recommended.
Sancuso Contraindications
Not Applicable
Sancuso Boxed Warnings
Not Applicable
Sancuso Warnings/Precautions
Warnings/Precautions
May mask progressive ilieus and/or gastric distention. Avoid direct sun or UV light (cover patch with clothing during use and for 10 days after removing patch). Avoid exposure to external heat sources (eg, heating pads). Pregnancy (Cat.B). Nursing mothers.
Sancuso Pharmacokinetics
See Literature
Sancuso Interactions
Interactions
Do not take with other granisetron products. Serotonin syndrome possible esp. with concomitant serotonergic drugs.
Sancuso Adverse Reactions
Adverse Reactions
Constipation; local irritation (remove patch if severe or if generalized skin reaction occurs), headache; serotonin syndrome (discontinue if occurs).
Sancuso Clinical Trials
See Literature
Sancuso Note
Not Applicable
Sancuso Patient Counseling
See Literature
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