Share on Facebook
Share on Twitter
Share on LinkedIn
Share by Email
Print
Promethazine Hcl Tablets Generic Name & Formulations
Legal Class
Rx
General Description
Promethazine HCl 12.5mg+, 25mg+, 50mg; tabs; +scored.
Pharmacological Class
Phenothiazine.
How Supplied
Contact supplier.
Manufacturer
Promethazine Hcl Tablets Indications
Indications
Motion sickness. Perioperative nausea & vomiting.
Promethazine Hcl Tablets Dosage and Administration
Adult
Motion sickness: 25mg 30–60mins before travel; may repeat in 8–12hrs; maintenance 25mg twice daily. Perioperative nausea & vomiting: 25mg; may give additional doses of 12.5–25mg at 4–6hr intervals.
Children
<2yrs: see Contraindications. Motion sickness: ≥2yrs: 12.5–25mg twice daily. Perioperative nausea & vomiting: 0.5mg/lb or 25mg; may give additional doses of 12.5–25mg or 0.5mg/lb at 4–6hr intervals.
Promethazine Hcl Tablets Contraindications
Contraindications
Children <2yrs. Dehydrated or ill children (esp. Reye's syndrome). History of sleep apnea. Asthma and lower respiratory disorders. Uncomplicated nausea in children.
Promethazine Hcl Tablets Boxed Warnings
Not Applicable
Promethazine Hcl Tablets Warnings/Precautions
Warnings/Precautions
Glaucoma. GI or urinary obstruction. Cardiovascular or liver disease. Seizure disorders. Peptic ulcer. Bone marrow depression. Elderly. Children ≥2yrs. Pregnancy (Cat.C). Nursing mothers: not recommended.
Promethazine Hcl Tablets Pharmacokinetics
See Literature
Promethazine Hcl Tablets Interactions
Interactions
Potentiates CNS depression with alcohol, other CNS depressants. Caution with MAOIs. May alter hCG pregnancy test results.
Promethazine Hcl Tablets Adverse Reactions
Adverse Reactions
Drowsiness, lowered seizure threshold, cholestatic jaundice, anticholinergic and extrapyramidal effects, photosensitivity, hypo- or hypertension, rash, blood dyscrasias, nausea, neonatal platelet abnormalities; children: respiratory depression (may be fatal).
Promethazine Hcl Tablets Clinical Trials
See Literature
Promethazine Hcl Tablets Note
Notes
Formerly known under the brand names Phenergan (tabs, supps); Promethacon (supps).
Promethazine Hcl Tablets Patient Counseling
See Literature
