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Nexium 24hr Generic Name & Formulations
Legal Class
OTC
General Description
Esomeprazole 20mg (equivalent to 22.3mg esomeprazole magnesium trihydrate); delayed-release caps; contains gelatin.
Pharmacological Class
Proton pump inhibitor.
How Supplied
Caps—14, 28, 42
Manufacturer
Nexium 24hr Indications
Indications
Frequent heartburn (≥2 days/week). Not intended for immediate relief of heartburn (may take 1–4 days for full effect).
Nexium 24hr Dosage and Administration
Adult
Swallow whole. Take before eating in the AM. ≥18yrs: 20mg once daily for 14 days; may repeat 14-day course every 4 months.
Children
<18yrs: not recommended.
Nexium 24hr Contraindications
Contraindications
Trouble or pain swallowing food. Vomiting with blood. Bloody or black stools. Chest or shoulder pain with shortness of breath; sweating; pain spreading to arms, neck, or shoulders; or lightheadedness. Frequent chest pain.
Nexium 24hr Boxed Warnings
Not Applicable
Nexium 24hr Warnings/Precautions
Warnings/Precautions
Heartburn >3 months. Frequent wheezing. Unexplained weight loss. Nausea/vomiting. Stomach pain. Discontinue and reevaluate if condition continues or worsens after 14 days, require >1 course of treatment every 4 months; diarrhea, rash, or joint pain develops. Pregnancy. Nursing mothers.
Nexium 24hr Pharmacokinetics
See Literature
Nexium 24hr Interactions
Interactions
May affect or be affected by blood-thinning agents (eg, warfarin, clopidogrel, cilostazol), antifungals, digoxin, diazepam, tacrolimus, mycophenolate mofetil, antiretrovirals, methotrexate.
Nexium 24hr Adverse Reactions
Adverse Reactions
Diarrhea, rash, joint pain; allergic or severe skin reactions (skin reddening, blisters).
Nexium 24hr Clinical Trials
See Literature
Nexium 24hr Note
Not Applicable
Nexium 24hr Patient Counseling
See Literature
