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Loperamide Generic Name & Formulations
Legal Class
OTC
General Description
Loperamide HCl 2mg; caps.
Pharmacological Class
Antidiarrheal.
How Supplied
Caps—contact supplier; A-D Caplets—6, 12, 18, 24; A-D Liq—2oz, 4oz; Caplets, Chew tabs—contact supplier
Manufacturer
Loperamide Indications
Indications
Diarrhea.
Loperamide Dosage and Administration
Adult
Acute: Initially 4mg, then 2mg after each loose stool; max 16mg/day. Stop after 48 hours if ineffective. Chronic: initially 4mg; maintenance 4–8mg/day. Reevaluate if no improvement after 10 days at 16mg/day.
Children
<2yrs: not recommended. 24–47lbs (2–5yrs): 1mg up to 3 times daily for 2 days (use liq). 48–59lbs (6–8yrs): initially 2mg, then 1mg after each loose stool; max 4mg/day for 2 days. 60–95lbs (9–11yrs): initially 2mg, then 1mg after each loose stool; max 6mg/day for 2 days.
Loperamide Contraindications
Contraindications
If constipation must be avoided. Acute dysentery.
Loperamide Boxed Warnings
Not Applicable
Loperamide Warnings/Precautions
Warnings/Precautions
Acute ulcerative colitis and antibiotic induced pseudomembranous colitis; discontinue if abdominal distention occurs. In dehydration, use fluid and electrolyte replacement. Serious cardiac effects or death if taking more than directed. History of abnormal heart rhythm. Hepatic dysfunction; monitor for CNS toxicity. Pregnancy (Cat.B). Nursing mothers.
Loperamide Pharmacokinetics
See Literature
Loperamide Interactions
Not Applicable
Loperamide Adverse Reactions
Adverse Reactions
Abdominal pain, distention, constipation, dry mouth, nausea, drowsiness, dizziness, fatigue, rash.
Loperamide Clinical Trials
See Literature
Loperamide Note
Notes
Formerly known under the brand name Imodium.
Loperamide Patient Counseling
See Literature
