Hyoscyamine Sulfate Drops Generic Name & Formulations
Legal Class
Rx
General Description
Hyoscyamine sulfate 0.125mg/mL; alcohol 5%; orange flavor.
Pharmacological Class
Anticholinergic.
How Supplied
Tabs, SL—100, 500; Drops—contact supplier
Manufacturer
Hyoscyamine Sulfate Drops Indications
Indications
Adjunct in peptic ulcer. Irritable bowel syndrome. Infant colic.
Hyoscyamine Sulfate Drops Dosage and Administration
Adult
1–2mL every 4 hrs or as needed; max 12mL/day.
Children
3.4kg: 4 drops. 5kg: 5 drops. 7kg: 6 drops. 10kg: 8 drops. Older children (2 yrs–12 yrs): 0.25–1mL; max 6mL/day. All: every 4 hrs or as needed.
Hyoscyamine Sulfate Drops Contraindications
Contraindications
Glaucoma. Unstable cardiovascular status in acute hemorrhage. GI or urinary tract obstruction. Paralytic ileus, intestinal atony of elderly or debilitated patients. Toxic megacolon. Severe ulcerative colitis. Myasthenia gravis.
Hyoscyamine Sulfate Drops Boxed Warnings
Not Applicable
Hyoscyamine Sulfate Drops Warnings/Precautions
Warnings/Precautions
High environmental temperature. Diarrhea. Autonomic neuropathy. Impaired cardiac or renal function. Cardiovascular disease. Hypertension. Hyperthyroidism. Hiatal hernia with reflux esophagitis. Pregnancy (Cat.C). Nursing mothers.
Hyoscyamine Sulfate Drops Pharmacokinetics
See Literature
Hyoscyamine Sulfate Drops Interactions
Interactions
Antacids may inhibit absorption. Additive anticholinergic effects with other anticholinergics, amantadine, type I antiarrhythmics, antihistamines, phenothiazines, tricyclics, MAOIs.
Hyoscyamine Sulfate Drops Adverse Reactions
Adverse Reactions
Anticholinergic effects, drowsiness.
Hyoscyamine Sulfate Drops Clinical Trials
See Literature
Hyoscyamine Sulfate Drops Note
Notes
Formerly known under the brand name Levsin Drops.
Hyoscyamine Sulfate Drops Patient Counseling
See Literature