Share on Facebook
Share on Twitter
Share on LinkedIn
Share by Email
Print
Granisetron Hcl Tablets Generic Name & Formulations
Legal Class
Rx
General Description
Granisetron HCl 1mg.
Pharmacological Class
Selective 5-HT3 receptor antagonist.
See Also
How Supplied
Contact supplier.
Manufacturer
Granisetron Hcl Tablets Indications
Indications
Prevention of nausea and vomiting associated with chemotherapy (including high-dose cisplatin), and with radiation (including total body irradiation and fractionated abdominal radiation).
Granisetron Hcl Tablets Dosage and Administration
Adult
Chemotherapy: give only on the days chemotherapy is given. 2mg up to 1 hour before chemotherapy; or, 1mg up to 1 hour before chemotherapy, then 1mg 12 hours after initial dose. Radiation: 2mg within 1 hour of radiation.
Children
Use IV form.
Granisetron Hcl Tablets Contraindications
Not Applicable
Granisetron Hcl Tablets Boxed Warnings
Not Applicable
Granisetron Hcl Tablets Warnings/Precautions
Warnings/Precautions
Abdominal surgery. May mask progressive ileus and/or gastric distention. Pre-existing arrhythmias or cardiac conduction disorders. Cardiac disease, concomitant cardio-toxic chemotherapy or electrolyte abnormalities: increased risk of QT prolongation. Pregnancy (Cat.B). Nursing mothers.
Granisetron Hcl Tablets Pharmacokinetics
See Literature
Granisetron Hcl Tablets Interactions
Interactions
Caution with drugs that affect CYP450 or prolong the QT interval.
Granisetron Hcl Tablets Adverse Reactions
Adverse Reactions
Headache, asthenia, diarrhea, constipation; QT prolongation.
Granisetron Hcl Tablets Clinical Trials
See Literature
Granisetron Hcl Tablets Note
Notes
Formerly known under the brand name Kytril.
Granisetron Hcl Tablets Patient Counseling
See Literature
