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Dificid Generic Name & Formulations
Legal Class
Rx
General Description
Fidaxomicin 200mg; tabs.
Pharmacological Class
Macrolide antibiotic.
See Also
How Supplied
Tabs—20; Susp—150mL
Manufacturer
Generic Availability
NO
Dificid Indications
Indications
Clostridioides difficile-associated diarrhea.
Dificid Dosage and Administration
Adult
Use tabs. ≥18yrs: 200mg twice daily for 10 days.
Children
<6months: not established. Use oral susp. Give twice daily for 10 days (w. oral dosing syringe). 6months–<18yrs (4–<7kg): 80mg; (7–<9kg): 120mg; (9–<12.5kg): 160mg; (≥12.5kg): 200mg (as oral susp or tabs if able to swallow).
Dificid Contraindications
Not Applicable
Dificid Boxed Warnings
Not Applicable
Dificid Warnings/Precautions
Warnings/Precautions
Not effective for treating other types of infections (minimal systemic absorption). Known macrolide allergy. Discontinue if severe hypersensitivity reactions occur. Pregnancy. Nursing mothers.
Dificid Pharmacokinetics
See Literature
Dificid Interactions
Not Applicable
Dificid Adverse Reactions
Adverse Reactions
Adults: nausea, vomiting, abdominal pain, GI hemorrhage, anemia, neutropenia; Children: pyrexia, abdominal pain, vomiting, diarrhea, constipation, increased aminotransferases, rash.
Dificid Clinical Trials
See Literature
Dificid Note
Not Applicable
Dificid Patient Counseling
See Literature
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