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Dartisla Odt Generic Name & Formulations
Legal Class
Rx
General Description
Glycopyrrolate 1.7mg; orally disintegrating tabs; black cherry-flavor.
Pharmacological Class
Anticholinergic.
How Supplied
Tabs—30
Manufacturer
Generic Availability
NO
Dartisla Odt Indications
Indications
To reduce symptoms of a peptic ulcer as an adjunct to treatment of peptic ulcer.
Limitations of Use
Not indicated as monotherapy for treatment of peptic ulcer because effectiveness in peptic ulcer healing has not been established.
Dartisla Odt Dosage and Administration
Adult
Use lowest effective dosage to control symptoms. Administer at least 1hr before or 2hrs after food. 1.7mg given two or three times daily. Max dose: 6.8mg/day. Allow tab to dissolve on the tongue; swallow without water. Patients receiving 2mg dose of another oral tab form of glycopyrrolate may switch to 1.7mg dose of Dartisla ODT. Patients on initial or maintenance treatment with a lower dosage strength of another oral glycopyrrolate product (eg, 1mg tab strength): Dartisla ODT is not recommended.
Children
Not established.
Dartisla Odt Contraindications
Contraindications
Glaucoma. Obstructive uropathies including prostatic hypertrophy. Mechanical obstructive diseases of GI tract (eg, pyloroduodenal stenosis, strictures). GI motility disorders (eg, achalasia, paralytic ileus, intestinal atony). Bleeding GI ulcer. Active inflammatory or infectious colitis that can lead to toxic megacolon. Toxic megacolon. Myasthenia gravis.
Dartisla Odt Boxed Warnings
Not Applicable
Dartisla Odt Warnings/Precautions
Warnings/Precautions
Discontinue if incomplete mechanical intestinal obstruction is suspected (diarrhea may be early symptom), symptoms of acute angle closure glaucoma, cognitive or visual impairment develop. Monitor for decreased GI motility. Conditions exacerbated by anticholinergic adverse reactions (eg, autonomic neuropathy, hyperthyroidism, cardiac disease, hiatal hernia associated with reflux esophagitis): not recommended. Avoid high environmental temperature. Renal impairment: monitor. Elderly: not recommended. Pregnancy. Nursing mothers.
Dartisla Odt Pharmacokinetics
See Literature
Dartisla Odt Interactions
Interactions
Additive anticholinergic effects with other anticholinergic drugs (eg, tricyclics, antiepileptics, type I antiarrhythmics, antispasmodics, amantadine). Concomitant with other anticholinergics or drugs that are affected by altered GI motility: not recommended. May worsen tardive dyskinesia with antipsychotics. May worsen GI mucosal injury with solid oral dosage forms of potassium chloride; avoid concomitant use.
Dartisla Odt Adverse Reactions
Adverse Reactions
Blurred vision, drowsiness, decreased sweating, flushing, vomiting, constipation, dry mouth, tachycardia, urinary retention.
Dartisla Odt Clinical Trials
See Literature
Dartisla Odt Note
Not Applicable
Dartisla Odt Patient Counseling
See Literature
