Cytotec Generic Name & Formulations
Legal Class
Rx
General Description
Misoprostol 100mcg, 200mcg; tabs.
Pharmacological Class
Prostaglandin E1 analogue.
How Supplied
Tabs 100mcg—60; 200mcg—60, 100
Manufacturer
Generic Availability
YES
Cytotec Indications
Indications
Prevention of NSAID-induced gastric ulcers.
Cytotec Dosage and Administration
Adult
Take with food. 200mcg 4 times daily with meals (last dose at bedtime). May reduce dose if not tolerated.
Children
Not established.
Cytotec Contraindications
Contraindications
Pregnancy.
Cytotec Boxed Warnings
Boxed Warning
Abortifacient property. Do not give the drug to others.
Cytotec Warnings/Precautions
Warnings/Precautions
Can cause birth defects, abortion, premature birth or uterine rupture in pregnant women. For women of childbearing potential: negative serum pregnancy test within 2 weeks before starting therapy; begin on 2nd or 3rd day of next menstrual period; maintain contraception during therapy; give oral and written warnings on risks in pregnancy. Cardiovascular disease. Inflammatory bowel disease. Dehydration. Labor & delivery. Nursing mothers.
Cytotec Pharmacokinetics
See Literature
Cytotec Interactions
Interactions
Avoid magnesium-containing antacids (to reduce diarrhea risk). Concomitant oxytocic agents: not recommended.
Cytotec Adverse Reactions
Adverse Reactions
Diarrhea, abdominal pain, headache, gynecological effects (eg, spotting, cramps), abortion, premature birth, birth defects, uterine rupture.
Cytotec Clinical Trials
See Literature
Cytotec Note
Not Applicable
Cytotec Patient Counseling
See Literature