Cytotec

— THERAPEUTIC CATEGORIES —
  • Hyperacidity, GERD, and ulcers

Cytotec Generic Name & Formulations

General Description

Misoprostol 100mcg, 200mcg; tabs.

Pharmacological Class

Prostaglandin E1 analogue.

How Supplied

Tabs 100mcg—60; 200mcg—60, 100

Manufacturer

Generic Availability

YES

Cytotec Indications

Indications

Prevention of NSAID-induced gastric ulcers.

Cytotec Dosage and Administration

Adult

Take with food. 200mcg 4 times daily with meals (last dose at bedtime). May reduce dose if not tolerated.

Children

Not established.

Cytotec Contraindications

Contraindications

Pregnancy.

Cytotec Boxed Warnings

Boxed Warning

Abortifacient property. Do not give the drug to others.

Cytotec Warnings/Precautions

Warnings/Precautions

Can cause birth defects, abortion, premature birth or uterine rupture in pregnant women. For women of childbearing potential: negative serum pregnancy test within 2 weeks before starting therapy; begin on 2nd or 3rd day of next menstrual period; maintain contraception during therapy; give oral and written warnings on risks in pregnancy. Cardiovascular disease. Inflammatory bowel disease. Dehydration. Labor & delivery. Nursing mothers.

Cytotec Pharmacokinetics

See Literature

Cytotec Interactions

Interactions

Avoid magnesium-containing antacids (to reduce diarrhea risk). Concomitant oxytocic agents: not recommended.

Cytotec Adverse Reactions

Adverse Reactions

Diarrhea, abdominal pain, headache, gynecological effects (eg, spotting, cramps), abortion, premature birth, birth defects, uterine rupture.

Cytotec Clinical Trials

See Literature

Cytotec Note

Not Applicable

Cytotec Patient Counseling

See Literature