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Chlorpromazine Generic Name & Formulations
Legal Class
Rx
General Description
Chlorpromazine HCl 10mg, 25mg, 50mg, 100mg, 200mg; tabs; contains parabens.
Pharmacological Class
Phenothiazine.
See Also
How Supplied
Contact supplier.
Manufacturer
Chlorpromazine Indications
Indications
Nausea and vomiting.
Chlorpromazine Dosage and Administration
Adult
10–25mg every 4–6hrs as needed.
Children
<6months: not recommended. ≥6months: 0.25mg/lb every 4–6hrs.
Chlorpromazine Contraindications
Contraindications
Coma. CNS or bone marrow depression. Reye's syndrome.
Chlorpromazine Boxed Warnings
Not Applicable
Chlorpromazine Warnings/Precautions
Warnings/Precautions
Discontinue 48 hrs before to 24 hrs after myelography. Cardiovascular, respiratory, renal, or liver disease. Epilepsy. Glaucoma. History of breast cancer. Exposure to extreme heat or organophosphates. Asthma (inj). Monitor blood, liver, and ocular function. Elderly. Pregnancy, nursing mothers: not recommended.
Chlorpromazine Pharmacokinetics
See Literature
Chlorpromazine Interactions
Interactions
Potentiates phenytoin, alcohol, other CNS depressants, propranolol. Potentiated by propranolol. Antagonized by anticholinergics. Atropine. Decreased guanethidine, anticoagulant effects.
Chlorpromazine Adverse Reactions
Adverse Reactions
Tardive dyskinesia, drowsiness, jaundice, blood dyscrasias, hypotension, retinopathy, may mask emetic signs of disease, lowered seizure threshold, rash, skin pigmentation, anticholinergic effects, insomnia, extrapyramidal reactions, neuroleptic malignant syndrome.
Chlorpromazine Clinical Trials
See Literature
Chlorpromazine Note
Notes
Formerly known under the brand name Thorazine.
Chlorpromazine Patient Counseling
See Literature
Chlorpromazine Generic Name & Formulations
Legal Class
Rx
General Description
Chlorpromazine HCl 10mg, 25mg, 50mg, 100mg, 200mg; tabs; contains parabens.
Pharmacological Class
Aliphatic phenothiazine.
See Also
How Supplied
Contact supplier.
Manufacturer
Chlorpromazine Indications
Indications
Psychosis. Mania. Intractable hiccups. Severe childhood behavior problems. Tetany.
Chlorpromazine Dosage and Administration
Adult
Psychosis: initially 10mg 3–4 (or 25mg 2–3) times daily; may increase semiweekly by 25–50mg daily. Hiccups: 25–50mg 3–4 times daily. Severe psychosis: initially 25mg 3 times daily; may increase semiweekly by 20–50mg/day.
Children
<6months: not recommended. ≥6months: initially 0.25mg/lb every 4–6hrs as needed.
Chlorpromazine Contraindications
Contraindications
Coma. CNS or bone marrow depression. Reye's syndrome.
Chlorpromazine Boxed Warnings
Not Applicable
Chlorpromazine Warnings/Precautions
Warnings/Precautions
Discontinue 48 hrs before to 24 hrs after myelography. Cardiovascular, respiratory, renal, or liver disease. Epilepsy. Glaucoma. History of breast cancer. Exposure to extreme heat or organophosphates. Asthma (inj). Monitor blood, liver, and ocular function. Elderly. Pregnancy, nursing mothers: not recommended.
Chlorpromazine Pharmacokinetics
See Literature
Chlorpromazine Interactions
Interactions
Potentiates phenytoin, alcohol, other CNS depressants, propranolol. Potentiated by propranolol. Antagonized by anticholinergics. Atropine. Decreased guanethidine, anticoagulant effects.
Chlorpromazine Adverse Reactions
Adverse Reactions
Tardive dyskinesia, drowsiness, jaundice, blood dyscrasias, hypotension, retinopathy, may mask emetic signs of disease, lowered seizure threshold, rash, skin pigmentation, anticholinergic effects, insomnia, extrapyramidal reactions, neuroleptic malignant syndrome.
Chlorpromazine Clinical Trials
See Literature
Chlorpromazine Note
Notes
Formerly known under the brand name Thorazine.
Chlorpromazine Patient Counseling
See Literature
