Carafate

— THERAPEUTIC CATEGORIES —
  • Hyperacidity, GERD, and ulcers

Carafate Generic Name & Formulations

General Description

Sucralfate 1g; scored tabs.

Pharmacological Class

Cytoprotective agent.

How Supplied

Tabs—100; Susp—14oz

Manufacturer

Carafate Indications

Indications

Short-term (up to 8 weeks) treatment of active duodenal ulcer. Maintenance of healed duodenal ulcers (tabs only).

Carafate Dosage and Administration

Adult

Active: 1g 4 times daily on an empty stomach for 4–8 weeks. Maintenance: 1g 2 times daily.

Children

Not established.

Carafate Contraindications

Not Applicable

Carafate Boxed Warnings

Not Applicable

Carafate Warnings/Precautions

Warnings/Precautions

Susp: administer by oral route only; do not give intravenously. Monitor for glycemia in diabetic patients. Chronic renal failure. Dialysis. Tabs: swallowing impairment (eg, recent or prolonged intubation, tracheostomy, history of aspiration, dysphagia, others). Pregnancy (Cat.B). Nursing mothers.

Carafate Pharmacokinetics

Elimination

Renal.

Carafate Interactions

Interactions

Avoid antacids within 30mins of dosing. May reduce absorption of tetracyclines, quinidine, levothyroxine, phenytoin, cimetidine, digoxin, ciprofloxacin, norfloxacin, ketoconazole, ranitidine, theophylline; dose concomitant drugs 2hrs before sucralfate. Additive aluminum load with aluminum-containing antacids. Monitor warfarin.

Carafate Adverse Reactions

Adverse Reactions

Constipation.

Carafate Clinical Trials

See Literature

Carafate Note

Not Applicable

Carafate Patient Counseling

See Literature