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Bonjesta Generic Name & Formulations
Legal Class
Rx
General Description
Doxylamine succinate 20mg, pyridoxine HCl 20mg; ext-rel tabs.
Pharmacological Class
Antihistamine + Vit. B6 analog.
How Supplied
Tabs—60, 100
Manufacturer
Generic Availability
NO
Bonjesta Indications
Indications
Nausea and vomiting of pregnancy in women who do not respond to conservative management.
Limitations of Use
Not studied in women with hyperemesis gravidarum.
Bonjesta Dosage and Administration
Adult
Swallow whole. Take on empty stomach with water. ≥18yrs: Day 1: initially 1 tab at bedtime; continue same dose next day if symptoms adequately controlled. If symptoms persist on Day 2, increase to 1 tab in AM and 1 tab at bedtime daily. Max 2 tabs daily.
Children
<18yrs: not established.
Bonjesta Contraindications
Contraindications
Concomitant MAOIs; may prolong and intensify anticholinergic effects.
Bonjesta Boxed Warnings
Not Applicable
Bonjesta Warnings/Precautions
Warnings/Precautions
Asthma. Increased intraocular pressure. Narrow angle glaucoma. Stenosing peptic ulcer. Pyloroduodenal obstruction. Urinary bladder-neck obstruction. Reevaluate as pregnancy progresses. Nursing mothers: not recommended.
Bonjesta Pharmacokinetics
See Literature
Bonjesta Interactions
Interactions
See Contraindications. Concomitant alcohol, other CNS depressants (eg, hypnotic sedatives, tranquilizers): not recommended. Concomitant food may delay onset of action and reduce absorption. May cause false (+) urine test for methadone, opiates, PCP.
Bonjesta Adverse Reactions
Adverse Reactions
Somnolence.
Bonjesta Clinical Trials
See Literature
Bonjesta Note
Not Applicable
Bonjesta Patient Counseling
See Literature
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