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Zegalogue Generic Name & Formulations
Legal Class
Rx
General Description
Dasiglucagon (as HCl) 0.6mg/0.6mL; soln for SC inj; preservative-free.
Pharmacological Class
Antihypoglycemic.
How Supplied
Single-dose prefilled syringe, single-dose autoinjector—1, 2
Manufacturer
Generic Availability
NO
Zegalogue Indications
Indications
Severe hypoglycemia.
Zegalogue Dosage and Administration
Adults and Children
<6yrs: not established. Give by SC inj into lower abdomen, buttocks, thighs, or outer upper arm. ≥6yrs: 0.6mg. May repeat if no response after 15mins. After responding, give oral carbohydrates.
Zegalogue Contraindications
Contraindications
Pheochromocytoma. Insulinoma.
Zegalogue Boxed Warnings
Not Applicable
Zegalogue Warnings/Precautions
Warnings/Precautions
Instruct caregivers in proper use. Previously undiagnosed pheochromocytoma. Lack of efficacy in insulinoma; may cause hypoglycemia. If hypoglycemia develops after treatment, give oral or IV glucose. Insufficient hepatic glycogen reserves (eg, starvation, adrenal insufficiency, chronic hypoglycemia); treat with glucose. Pregnancy. Nursing mothers.
Zegalogue Pharmacokinetics
See Literature
Zegalogue Interactions
Interactions
Transient increase in pulse and blood pressure may occur with beta-blockers. Loss of efficacy or may produce hypoglycemia with indomethacin. May potentiate the anticoagulant effect of warfarin.
Zegalogue Adverse Reactions
Adverse Reactions
Nausea, vomiting, headache, inj site pain; adults also: diarrhea; hypersensitivity reactions.
Zegalogue Clinical Trials
See Literature
Zegalogue Note
Not Applicable
Zegalogue Patient Counseling
See Literature
