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Veripred 20 Generic Name & Formulations
Legal Class
Rx
General Description
Prednisolone (as sodium phosphate) 20mg/5mL; soln; dye- and alcohol-free; grape-flavor.
Pharmacological Class
Glucocorticoid.
How Supplied
Soln—8oz
Manufacturer
Veripred 20 Indications
Indications
Steroid-responsive disorders.
Veripred 20 Dosage and Administration
Adult
See literature. Individualize. Initially 5–60mg/day.
Children
See literature. Individualize. Initially 0.14–2mg/kg/day in 3–4 divided doses.
Veripred 20 Contraindications
Contraindications
Systemic fungal infections. Live vaccines.
Veripred 20 Boxed Warnings
Not Applicable
Veripred 20 Warnings/Precautions
Warnings/Precautions
May increase risk and mask signs of infection. Tuberculosis. Latent amebiasis. Strongyloides infestation. Ocular herpes simplex. Cerebral malaria. If exposed to chickenpox or measles, consider prophylaxis with immunoglobulin. Supplement with additional steroids in physiologic stress. Hypertension. Renal insufficiency. CHF. Hypothyroidism. Cirrhosis. Kaposi's sarcoma. Ulcerative colitis if perforation pending. Peptic ulcer. Diverticulitis. Intestinal anastomoses. Myasthenia gravis. Osteoporosis. Diabetes. Avoid abrupt cessation. May cause electrolyte imbalances, adrenocortical insufficiency, psychotic derangements. Use lowest effective dose. Monitor weight, growth, fluid and electrolyte balance, intraocular pressure. Elderly. Pregnancy (Cat.C). Nursing mothers.
Veripred 20 Pharmacokinetics
See Literature
Veripred 20 Interactions
Interactions
Barbiturates, hydantoins, rifampin, ephedrine, other hepatic enzyme inducers may decrease effects. Potentiated by ketoconazole, estrogens (eg, oral contraceptives). Potentiates and potentiated by cyclosporine. Increased risk of GI effects with aspirin or other NSAIDs. Monitor oral anticoagulants. Excretion of salicylates may be increased. Caution with K+ depleting agents (eg, diuretics, amphotericin-B), digoxin, aspirin in hypoprothrombinemia. Withdraw anticholinesterases at least 24 hours before starting steroids. Adjust antidiabetic agents. May suppress reactions to skin tests.
Veripred 20 Adverse Reactions
Adverse Reactions
HPA axis suppression, increased susceptibility to infection, glaucoma, cataracts, secondary infections, hypokalemia, hypocalcemia, hypernatremia, hypertension, CHF, psychic disorders, myopathy, osteoporosis, peptic ulcer, dermal atrophy, increased intracranial pressure, carbohydrate intolerance.
Veripred 20 Clinical Trials
See Literature
Veripred 20 Note
Not Applicable
Veripred 20 Patient Counseling
See Literature
