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Methimazole Generic Name & Formulations
Legal Class
Rx
General Description
Methimazole 5mg, 10mg; scored tabs.
Pharmacological Class
Antithyroid.
How Supplied
Contact supplier
Manufacturer
Methimazole Indications
Indications
Hyperthyroidism.
Methimazole Dosage and Administration
Adult
Initially 15–60mg daily in 3 divided doses, depending on severity of disease. Maintenance: 5–15mg daily.
Children
Initially 0.4mg/kg daily in 3 divided doses. Maintenance: ½ initial dose.
Methimazole Contraindications
Contraindications
Nursing mothers.
Methimazole Boxed Warnings
Not Applicable
Methimazole Warnings/Precautions
Warnings/Precautions
Discontinue if agranulocytosis, aplastic anemia, exfoliate dermatitis, hepatitis, or elevated liver transaminases (3xULN) occurs. Monitor prothrombin time, WBC, bone marrow function. Pregnancy (Cat.D).
Methimazole Pharmacokinetics
See Literature
Methimazole Interactions
Interactions
Potentiates anticoagulants.
Methimazole Adverse Reactions
Adverse Reactions
Rash, GI disturbances, arthralgia, paresthesia, hair and taste loss, agranulocytosis, blood dyscrasias, aplastic anemia, hepatic dysfunction, drug fever, lupus-like syndrome, insulin autoimmune syndrome, periarteritis; nephritis (rare).
Methimazole Clinical Trials
See Literature
Methimazole Note
Notes
Formerly known under the brand name Tapazole.
Methimazole Patient Counseling
See Literature
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