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Cytomel Generic Name & Formulations
Legal Class
Rx
General Description
Liothyronine sodium 5mcg, 25mcg, 50mcg; tabs.
Pharmacological Class
T3 (synthetic).
How Supplied
Tabs—100
Manufacturer
Cytomel Indications
Indications
Hypothyroidism.
Cytomel Dosage and Administration
Adult
Hypothyroidism: initially 25mcg daily; may increase by up to 25mcg every 1–2 weeks; usual maintenance 25–75mcg daily. Myxedema, simple goiter: initially 5mcg daily; may increase by 5–10mcg daily every 1–2 weeks to 25mcg daily, then may increase by 5–25mcg every 1–2 weeks (myxedema) or by 12.5 or 25mcg daily every 1–2 weeks (simple goiter). Maintenance: myxedema: 50–100mcg/day; simple goiter: 75mcg/day.
Children
Initially 5mcg daily; may increase by 5mcg daily every 3–4 days. Cretinism: maintenance dose: <1yr: 20mcg/day. 1–3yrs: 50mcg/day. >3yrs: as adult.
Cytomel Contraindications
Contraindications
Uncorrected adrenocortical insufficiency. Untreated thyrotoxicosis.
Cytomel Boxed Warnings
Boxed Warning
Larger doses particularly when given concomitantly with sympathomimetic amines for anorectic effects may produce serious or life-threatening toxicity.
Cytomel Warnings/Precautions
Warnings/Precautions
Not for treatment of obesity or infertility (unless with hypothyroidism). Cardiovascular disease, angina, elderly: use lower initial dose. Adrenocortical insufficiency. Diabetes. Monitor for craniosynostosis in infants. Pregnancy (Cat.A). Nursing mothers.
Cytomel Pharmacokinetics
See Literature
Cytomel Interactions
Interactions
Monitor oral anticoagulants, hypoglycemics, digoxin. Estrogens affect thyroid function tests. Monitor for hypertension with ketamine. Toxicity with larger doses of sympathomimetics (eg, anorectics).
Cytomel Adverse Reactions
Adverse Reactions
Hyperthyroidism, transient hair loss in children.
Cytomel Clinical Trials
See Literature
Cytomel Note
Not Applicable
Cytomel Patient Counseling
See Literature
