Cabergoline

— THERAPEUTIC CATEGORIES —
  • Pituitary disorders

Cabergoline Generic Name & Formulations

General Description

Cabergoline 0.5mg; scored tabs.

Pharmacological Class

Dopamine agonist.

How Supplied

Contact supplier.

Cabergoline Indications

Indications

Hyperprolactinemic disorders, either idiopathic or due to pituitary tumors.

Cabergoline Dosage and Administration

Adult

Initially 0.25mg twice weekly. Dose may be increased at 4-week intervals by 0.25mg twice weekly. Max: 1mg twice weekly.

Children

Not established.

Cabergoline Contraindications

Contraindications

Uncontrolled hypertension. Sensitivity to ergot alkaloids.

Cabergoline Boxed Warnings

Not Applicable

Cabergoline Warnings/Precautions

Warnings/Precautions

Not for pregnancy-induced hypertension or postpartum lactation inhibition or suppression. Respiratory or cardiac disease due to fibrosis. Psychiatric disorders (eg, impulse control/compulsive behaviors, pathological gambling, increased libido). Hepatic impairment. Pregnancy. Nursing mothers: not recommended.

Cabergoline Pharmacokinetics

See Literature

Cabergoline Interactions

Interactions

Concurrent dopamine D2 antagonists (eg, phenothiazines, butyrophenones, thioxanthines, metoclopramide): not recommended. Hypotension may be potentiated by antihypertensives.

Cabergoline Adverse Reactions

Adverse Reactions

GI upset, dizziness, fatigue, postural hypotension, nervousness, breast pain, dysmenorrhea, vision abnormalities; rare: fibrosis, valvulopathy.

Cabergoline Clinical Trials

See Literature

Cabergoline Note

Notes

Formerly known under the brand name Dostinex.

Cabergoline Patient Counseling

See Literature