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Vueway Generic Name & Formulations
Legal Class
General Description
Pharmacological Class
How Supplied
Single-dose vials (3mL, 7.5mL, 10mL, 15mL)—1, 10; Single-dose prefilled syringes (7.5mL, 10mL, 15mL)—1, 10
Manufacturer
Generic Availability
NO
Vueway Indications
Indications
For use in MRI of the CNS (brain, spine, and associated tissues) and the body (head, neck, thorax, abdomen, pelvis, and musculoskeletal system) in adults and children to detect and visualize lesions with abnormal vascularity.
Vueway Dosage and Administration
Adults and Children
<2yrs: not established. Give by IV bolus inj at a rate of ~2mL/sec manually or by compatible power injector. ≥2yrs: 0.05mmol/kg (0.1mL/kg), followed by a normal saline IV flush.
Vueway Contraindications
Not Applicable
Vueway Boxed Warnings
Boxed Warning
Nephrogenic systemic fibrosis.
Vueway Warnings/Precautions
Warnings/Precautions
Increased risk for nephrogenic systemic fibrosis in chronic kidney disease or acute kidney injury; avoid use. Screen for renal dysfunction. Do not exceed recommended dose and allow sufficient time for drug elimination before re-administration. Have emergency resuscitative equipment available. History of asthma or other allergic disorders. Monitor for signs/symptoms of hypersensitivity reactions during and after administration. Increased risk of gadolinium retention with multiple lifetime doses, in pregnant patients, children, and those with inflammatory conditions; minimize repetitive imaging studies. Avoid extravasation. Interpreting Vueway MRI scans without a companion non-contrast MRI. Renal impairment. Elderly. Pregnancy. Nursing mothers.
Vueway Pharmacokinetics
Distribution
The mean (CV%) volume of distribution at steady state is 13 (13%) L.
Plasma protein bound ≤1.8%.
Elimination
Renal (~98%). Half-life: 1.5 hours.
Vueway Interactions
Not Applicable
Vueway Adverse Reactions
Adverse Reactions
Inj site pain, headache, nausea, inj site warmth and coldness, dizziness, localized swelling.
Vueway Clinical Trials
See Literature
Vueway Note
Not Applicable
Vueway Patient Counseling
See Literature
