Omnipaque Oral Solution 9

— THERAPEUTIC CATEGORIES —
  • Imaging agents

Omnipaque Oral Solution 9 Generic Name & Formulations

General Description

Iohexol 19mg (equivalent to 9mg of organic iodine) per mL; preservative-free.

Pharmacological Class

Radiographic contrast medium.

How Supplied

Oral soln (500mL)—10

Manufacturer

Generic Availability

NO

Omnipaque Oral Solution 9 Indications

Indications

In conjunction with Omnipaque 240 or 300 intravenous injection, for computerized tomography (CT) of the abdomen.

Omnipaque Oral Solution 9 Dosage and Administration

Adult

For oral use only. Give all at once or over a period of up to 45mins. 500–1000mL. See full labeling for concomitant Omnipaque 300 IV inj dosing.

Children

For oral use only. Give all at once or over a period of up to 45mins. 180–750mL. Max oral iodine (<3yrs): 5g; (3–18yrs): 10g. See full labeling for concomitant Omnipaque 240 or 300 IV inj dosing.

Omnipaque Oral Solution 9 Contraindications

Contraindications

Parenteral administration.

Omnipaque Oral Solution 9 Boxed Warnings

Not Applicable

Omnipaque Oral Solution 9 Warnings/Precautions

Warnings/Precautions

Hemolysis may occur if administered intravascularly. Have emergency treatment and trained personnel readily available. Monitor for hypersensitivity reactions. Thyroid dysfunction (esp. children 0–3yrs); monitor. Ensure adequate hydration. Elderly. Pregnancy. Nursing mothers: consider interrupting; pump/discard breast milk for 10hrs after administration.

Omnipaque Oral Solution 9 Pharmacokinetics

See Literature

Omnipaque Oral Solution 9 Interactions

Interactions

See full labeling. Discontinue metformin at time of, or prior to Omnipaque in patients with eGFR 30–60mL/min/1.73m2, history of hepatic impairment, alcoholism, heart failure, or will be given intra-arterial contrast; reevaluate eGFR 48hrs after procedure and restart metformin if renally stable. Discontinue CNS active drugs (eg, MAOIs, tricyclics, CNS stimulants, analeptics, tranquilizers, antipsychotics) ≥48hrs before myelography and for ≥24hrs post-procedure. Caution with beta-blockers. May interfere with thyroid uptake of radioactive iodine and decrease efficacy in thyroid carcinoma for up to 6–8 weeks. May reduce iodine-binding capacity of thyroid tissue for up to 2 weeks.

Omnipaque Oral Solution 9 Adverse Reactions

Adverse Reactions

Vomiting.

Omnipaque Oral Solution 9 Clinical Trials

See Literature

Omnipaque Oral Solution 9 Note

Not Applicable

Omnipaque Oral Solution 9 Patient Counseling

See Literature