Omnipaque Oral Solution 12 Generic Name & Formulations
Legal Class
Rx
General Description
Iohexol 26mg (equivalent to 12mg of organic iodine) per mL; preservative-free.
Pharmacological Class
Radiographic contrast medium.
See Also
How Supplied
Oral soln (500mL)—10
Manufacturer
Generic Availability
NO
Omnipaque Oral Solution 12 Indications
Indications
In conjunction with Omnipaque 240 or 300 intravenous injection, for computerized tomography (CT) of the abdomen.
Omnipaque Oral Solution 12 Dosage and Administration
Adult
For oral use only. Give all at once or over a period of up to 45mins. 500–1000mL. See full labeling for concomitant Omnipaque 300 IV inj dosing.
Children
For oral use only. Give all at once or over a period of up to 45mins. 180–750mL. Max oral iodine (<3yrs): 5g; (3–18yrs): 10g. See full labeling for concomitant Omnipaque 240 or 300 IV inj dosing.
Omnipaque Oral Solution 12 Contraindications
Contraindications
Parenteral administration.
Omnipaque Oral Solution 12 Boxed Warnings
Not Applicable
Omnipaque Oral Solution 12 Warnings/Precautions
Warnings/Precautions
Hemolysis may occur if administered intravascularly. Have emergency treatment and trained personnel readily available. Monitor for hypersensitivity reactions. Thyroid dysfunction (esp. children 0–3yrs); monitor. Ensure adequate hydration. Elderly. Pregnancy. Nursing mothers: consider interrupting; pump/discard breast milk for 10hrs after administration.
Omnipaque Oral Solution 12 Pharmacokinetics
See Literature
Omnipaque Oral Solution 12 Interactions
Interactions
See full labeling. Discontinue metformin at time of, or prior to Omnipaque in patients with eGFR 30–60mL/min/1.73m2, history of hepatic impairment, alcoholism, heart failure, or will be given intra-arterial contrast; reevaluate eGFR 48hrs after procedure and restart metformin if renally stable. Discontinue CNS active drugs (eg, MAOIs, tricyclics, CNS stimulants, analeptics, tranquilizers, antipsychotics) ≥48hrs before myelography and for ≥24hrs post-procedure. Caution with beta-blockers. May interfere with thyroid uptake of radioactive iodine and decrease efficacy in thyroid carcinoma for up to 6–8 weeks. May reduce iodine-binding capacity of thyroid tissue for up to 2 weeks.
Omnipaque Oral Solution 12 Adverse Reactions
Adverse Reactions
Vomiting.
Omnipaque Oral Solution 12 Clinical Trials
See Literature
Omnipaque Oral Solution 12 Note
Not Applicable
Omnipaque Oral Solution 12 Patient Counseling
See Literature