Omnipaque Oral Solution 12

— THERAPEUTIC CATEGORIES —
  • Imaging agents

Omnipaque Oral Solution 12 Generic Name & Formulations

General Description

Iohexol 26mg (equivalent to 12mg of organic iodine) per mL; preservative-free.

Pharmacological Class

Radiographic contrast medium.

How Supplied

Oral soln (500mL)—10

Manufacturer

Generic Availability

NO

Omnipaque Oral Solution 12 Indications

Indications

In conjunction with Omnipaque 240 or 300 intravenous injection, for computerized tomography (CT) of the abdomen.

Omnipaque Oral Solution 12 Dosage and Administration

Adult

For oral use only. Give all at once or over a period of up to 45mins. 500–1000mL. See full labeling for concomitant Omnipaque 300 IV inj dosing.

Children

For oral use only. Give all at once or over a period of up to 45mins. 180–750mL. Max oral iodine (<3yrs): 5g; (3–18yrs): 10g. See full labeling for concomitant Omnipaque 240 or 300 IV inj dosing.

Omnipaque Oral Solution 12 Contraindications

Contraindications

Parenteral administration.

Omnipaque Oral Solution 12 Boxed Warnings

Not Applicable

Omnipaque Oral Solution 12 Warnings/Precautions

Warnings/Precautions

Hemolysis may occur if administered intravascularly. Have emergency treatment and trained personnel readily available. Monitor for hypersensitivity reactions. Thyroid dysfunction (esp. children 0–3yrs); monitor. Ensure adequate hydration. Elderly. Pregnancy. Nursing mothers: consider interrupting; pump/discard breast milk for 10hrs after administration.

Omnipaque Oral Solution 12 Pharmacokinetics

See Literature

Omnipaque Oral Solution 12 Interactions

Interactions

See full labeling. Discontinue metformin at time of, or prior to Omnipaque in patients with eGFR 30–60mL/min/1.73m2, history of hepatic impairment, alcoholism, heart failure, or will be given intra-arterial contrast; reevaluate eGFR 48hrs after procedure and restart metformin if renally stable. Discontinue CNS active drugs (eg, MAOIs, tricyclics, CNS stimulants, analeptics, tranquilizers, antipsychotics) ≥48hrs before myelography and for ≥24hrs post-procedure. Caution with beta-blockers. May interfere with thyroid uptake of radioactive iodine and decrease efficacy in thyroid carcinoma for up to 6–8 weeks. May reduce iodine-binding capacity of thyroid tissue for up to 2 weeks.

Omnipaque Oral Solution 12 Adverse Reactions

Adverse Reactions

Vomiting.

Omnipaque Oral Solution 12 Clinical Trials

See Literature

Omnipaque Oral Solution 12 Note

Not Applicable

Omnipaque Oral Solution 12 Patient Counseling

See Literature