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Nephroscan Generic Name & Formulations
Legal Class
Rx
General Description
Technetium Tc 99m succimer 1mg; per vial; lyophilized pwd for IV inj after reconstitution. After radiolabeling (with sodium pertechnetate Tc 99m + dilution), contains up to 1480MBq (40mCi) of technetium Tc 99m succimer in approx. 5mL volume.
Pharmacological Class
Radioactive diagnostic agent.
How Supplied
Kit—1 (5 single-dose vials)
Manufacturer
Generic Availability
NO
Nephroscan Indications
Indications
As an aid in the scintigraphic evaluation of renal parenchymal disorders.
Nephroscan Dosage and Administration
Adult
See full labeling. Give by IV inj (bolus). Administer 74–222MBq (2–6mCi). Begin image acquisition 1–4hrs post-inj. Severely reduced eGFR: delay image acquisition up to 6–24hrs.
Children
See full labeling. Give by IV inj (bolus). Base dose on body wt. Administer 1.85MBq/kg (0.05mCi/kg) with a range of 19–74MBq (0.5–2mCi). Begin image acquisition 1–4hrs post-inj. Severely reduced eGFR: delay image acquisition up to 6–24hrs.
Nephroscan Contraindications
Not Applicable
Nephroscan Boxed Warnings
Not Applicable
Nephroscan Warnings/Precautions
Warnings/Precautions
Risk of radiation exposure. Should only be used by trained and experienced physicians in the safe use and handling of radionuclides to minimize radiation exposure. Have resuscitation equipment/medications readily available. Ensure adequate hydration; encourage frequent voiding post-administration. Advanced renal failure: may have an effect on image interpretation. Elderly. Pregnancy. Nursing mothers: interrupt and pump/discard breastmilk for at least 24hrs after administration.
Nephroscan Pharmacokinetics
See Literature
Nephroscan Interactions
Not Applicable
Nephroscan Adverse Reactions
Adverse Reactions
Urticaria, rash, pruritus, erythema, syncope, fever, nausea; hypersensitivity reactions.
Nephroscan Clinical Trials
See Literature
Nephroscan Note
Not Applicable
Nephroscan Patient Counseling
See Literature
