Share on Facebook
Share on Twitter
Share on LinkedIn
Share by Email
Print
Lumason Generic Name & Formulations
Legal Class
Rx
General Description
Sulfur hexafluoride lipid-type A microspheres (25mg of lipid-type A lyophilized pwd with 60.7mg of sulfur hexafluoride gas); per vial; susp for IV or intravesical inj after reconstitution.
Pharmacological Class
Contrast media.
How Supplied
Kit—1 (one vial + diluent + mini-spike)
Manufacturer
Generic Availability
NO
Lumason Indications
Indications
In adults and children with suboptimal echocardiograms to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border. In ultrasonography of the liver to characterize focal liver lesions in adults and children. In ultrasonography of the urinary tract for evaluation of suspected or known vesicoureteral reflux in children.
Lumason Dosage and Administration
Adult
See full labeling. Echocardiography: 2mL via IV bolus inj. Ultrasonography of the liver: 2.4mL via IV inj. Both: may repeat dose once if needed. Follow each inj with 5mL normal saline flush.
Children
See full labeling. Echocardiography: 0.03mL/kg via IV inj; max 2mL per inj. Ultrasonography of the liver: 0.03mL/kg via IV inj; max 2.4mL per inj. Both: may repeat dose once if needed. Follow each inj with 5mL normal saline flush. Ultrasonography of the urinary tract: 1mL via intravesical bolus inj through the urinary catheter. The bladder may be refilled with normal saline for second cycle of voiding and imaging, without the need of a second Lumason inj.
Lumason Contraindications
Not Applicable
Lumason Boxed Warnings
Boxed Warning
Serious cardiopulmonary reactions.
Lumason Warnings/Precautions
Warnings/Precautions
Do not administer by intra-arterial inj. Risk of serious cardiopulmonary reactions; increased risk in those with unstable conditions (eg, acute MI, coronary artery syndromes, CHF, ventricular arrhythmias). Have resuscitation equipment and trained personnel readily available. Monitor for hypersensitivity reactions. Assess for prior hypersensitivity to PEG (eg, bowel preps, laxatives). Assess patients with cardiac shunts for embolic phenomena post inj. Not recommended for use at mechanical indices >0.8; high index values may lead to ventricular arrhythmias. Pregnancy. Nursing mothers.
Lumason Pharmacokinetics
See Literature
Lumason Interactions
Not Applicable
Lumason Adverse Reactions
Adverse Reactions
Headache, nausea, dysgeusia, inj site pain, feeling hot; cardiopulmonary reactions, anaphylaxis.
Lumason Clinical Trials
See Literature
Lumason Note
Not Applicable
Lumason Patient Counseling
See Literature
