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Cortrosyn Generic Name & Formulations
Legal Class
Rx
General Description
Cosyntropin 0.25mg/mL; pwd for IV or IM inj after reconstitution; preservative-free.
Pharmacological Class
Synthetic ACTH.
How Supplied
Vials—10
Manufacturer
Cortrosyn Indications
Indications
For use in the screening of patients presumed to have adrenocortical insufficiency.
Cortrosyn Dosage and Administration
Adults and Children
Give by IV, IM inj or IV infusion over 4–8hrs. <2yrs: 0.125mg. ≥2yrs: Usual range: 0.25–0.75mg.
Cortrosyn Contraindications
Not Applicable
Cortrosyn Boxed Warnings
Not Applicable
Cortrosyn Warnings/Precautions
Warnings/Precautions
Patients with raised bilirubin or where plasma contains free hemoglobin: falsely high fluorescence measurements may result. Pregnancy (Cat.C). Nursing mothers.
Cortrosyn Pharmacokinetics
See Literature
Cortrosyn Interactions
Interactions
May accentuate the electrolyte loss associated with diuretics. May exhibit abnormally high plasma cortisol levels if patients taking cortisone, hydrocortisone, spironolactone, estrogens.
Cortrosyn Adverse Reactions
Adverse Reactions
Hypersensitivity reactions (eg, rare, but possible), bradycardia, tachycardia, hypertension, peripheral edema, rash.
Cortrosyn Clinical Trials
See Literature
Cortrosyn Note
Not Applicable
Cortrosyn Patient Counseling
See Literature
