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Zonalon Generic Name & Formulations
Legal Class
Rx
General Description
Doxepin HCl 5%; crm.
Pharmacological Class
Antipruritic.
How Supplied
Crm—30g, 45g
Manufacturer
Zonalon Indications
Indications
Moderate pruritus associated with atopic dermatitis and lichen simplex chronicus.
Zonalon Dosage and Administration
Adult
Apply thin film to affected area 4 times a day at 3–4 hour intervals for up to 8 days. Do not occlude.
Children
Not recommended.
Zonalon Contraindications
Contraindications
Untreated narrow-angle glaucoma. Urinary retention.
Zonalon Boxed Warnings
Not Applicable
Zonalon Warnings/Precautions
Warnings/Precautions
During or within 14 days of MAOIs. Poor metabolizers may have increased effects. For dermatological use only. Avoid eyes. Pregnancy (Cat.B). Nursing mothers: not recommended.
Zonalon Pharmacokinetics
See Literature
Zonalon Interactions
Interactions
Discontinue MAOIs at least 2 weeks before starting. Alcohol, CNS depressants potentiate sedation. May potentiate drugs metabolized by CYP2D6 (eg, cimetidine, tricyclic antidepressants, SSRIs, phenothiazines, carbamazepine, propafenone, flecainide, encainide, quinidine).
Zonalon Adverse Reactions
Adverse Reactions
Drowsiness, dry mouth, thirst, headache, fatigue, dizziness, emotional or taste changes, burning/stinging, pruritus or eczema exacerbation, skin dryness or tightening, parethesias, edema.
Zonalon Clinical Trials
See Literature
Zonalon Note
Not Applicable
Zonalon Patient Counseling
See Literature
Zonalon Generic Name & Formulations
Legal Class
Rx
General Description
Doxepin HCl 5%; crm.
Pharmacological Class
Antipruritic.
How Supplied
Crm—30g, 45g
Manufacturer
Zonalon Indications
Indications
Moderate pruritus associated with atopic dermatitis and lichen simplex chronicus.
Zonalon Dosage and Administration
Adult
Apply thin film to affected area 4 times a day at 3–4 hour intervals for up to 8 days. Do not occlude.
Children
Not recommended.
Zonalon Contraindications
Contraindications
Untreated narrow-angle glaucoma. Urinary retention.
Zonalon Boxed Warnings
Not Applicable
Zonalon Warnings/Precautions
Warnings/Precautions
During or within 14 days of MAOIs. Poor metabolizers may have increased effects. For dermatological use only. Avoid eyes. Pregnancy (Cat.B). Nursing mothers: not recommended.
Zonalon Pharmacokinetics
See Literature
Zonalon Interactions
Interactions
Discontinue MAOIs at least 2 weeks before starting. Alcohol, CNS depressants potentiate sedation. May potentiate drugs metabolized by CYP2D6 (eg, cimetidine, tricyclic antidepressants, SSRIs, phenothiazines, carbamazepine, propafenone, flecainide, encainide, quinidine).
Zonalon Adverse Reactions
Adverse Reactions
Drowsiness, dry mouth, thirst, headache, fatigue, dizziness, emotional or taste changes, burning/stinging, pruritus or eczema exacerbation, skin dryness or tightening, parethesias, edema.
Zonalon Clinical Trials
See Literature
Zonalon Note
Not Applicable
Zonalon Patient Counseling
See Literature
