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Ziana Generic Name & Formulations
Legal Class
Rx
General Description
Clindamycin phosphate 1.2%; tretinoin 0.025%; gel.
Pharmacological Class
Lincosamide + retinoid.
How Supplied
Gel—2g, 30g, 60g
Manufacturer
Ziana Indications
Indications
Acne vulgaris.
Ziana Dosage and Administration
Adult
Apply thin film to clean, dry face once daily at bedtime.
Children
Not recommended.
Ziana Contraindications
Contraindications
Regional enteritis. Ulcerative colitis. History of antibiotic-associated colitis.
Ziana Boxed Warnings
Not Applicable
Ziana Warnings/Precautions
Warnings/Precautions
Sunburn (allow to heal before using). Avoid sun, UV light, eyes, mouth, angles of nose, mucous membranes. Discontinue if significant diarrhea occurs. Increased irritation in extreme weather. Pregnancy (Cat.C). Nursing mothers: not recommended.
Ziana Pharmacokinetics
See Literature
Ziana Interactions
Interactions
Avoid erythromycin. Additive irritation with other topical products (eg, alcohol, drying agents, lime). May potentiate neuromuscular blockers. Caution with other photosensitizers (eg, tetracyclines, quinolones).
Ziana Adverse Reactions
Adverse Reactions
Erythema, scaling, itching, burning, stinging, nasopharyngitis, throat pain, dry skin, cough, sinusitis; rare: diarrhea, colitis.
Ziana Clinical Trials
See Literature
Ziana Note
Not Applicable
Ziana Patient Counseling
See Literature
