Tetracycline

— THERAPEUTIC CATEGORIES —
  • Acne
  • Bacterial infections

Tetracycline Generic Name & Formulations

General Description

Tetracycline HCl 250mg, 500mg; caps.

Pharmacological Class

Tetracycline antibiotic.

How Supplied

Contact supplier.

Tetracycline Indications

Indications

Adjunct in severe acne.

Tetracycline Dosage and Administration

Adult

Take with fluids, 1 hour before or 2 hours after meals. Initially 1g daily in 2–4 divided doses. After improvement: 125–500mg daily.

Children

Not recommended.

Tetracycline Contraindications

Not Applicable

Tetracycline Boxed Warnings

Not Applicable

Tetracycline Warnings/Precautions

Warnings/Precautions

Renal impairment. Monitor blood, renal and hepatic function in long-term use. Avoid sun and UV light. Discontinue if skin erythema occurs. Pregnancy (Cat.D), nursing mothers: not recommended.

Tetracycline Pharmacokinetics

See Literature

Tetracycline Interactions

Interactions

Avoid methoxyflurane, photosensitizing agents. May antagonize bactericidal antibiotics; avoid. Reduced absorption with antacids, iron, zinc, calcium, magnesium, dairy products, urinary alkalinizers, other multivalent cations. May reduce effectiveness of oral contraceptives. Monitor prothrombin time with oral anticoagulants.

Tetracycline Adverse Reactions

Adverse Reactions

Photosensitivity, GI upset, rash, blood dyscrasias, increased BUN, hepatotoxicity; rare: esophagitis and esophageal ulceration.

Tetracycline Clinical Trials

See Literature

Tetracycline Note

Notes

Formerly known under the brand names Achromycin V, Tetracyn, Tetrex.

Tetracycline Patient Counseling

See Literature

Tetracycline Generic Name & Formulations

General Description

Tetracycline HCl 250mg, 500mg; caps.

Pharmacological Class

Tetracycline antibiotic.

How Supplied

Contact supplier.

Tetracycline Indications

Indications

Tetracycline-sensitive infections, including respiratory, genitourinary, skin and soft tissue, and those caused by rickettsiae and Mycoplasma pneumoniae; also cholera, psittacosis, plague, shigellosis.

Tetracycline Dosage and Administration

Adult

Take with fluids, 1 hour before or 2 hours after meals. 250–500mg 4 times daily.

Children

<8yrs: not recommended. Take with fluids, 1 hour before or 2 hours after meals. ≥8yrs: 25–50mg/kg/day in 4 divided doses.

Tetracycline Contraindications

Not Applicable

Tetracycline Boxed Warnings

Not Applicable

Tetracycline Warnings/Precautions

Warnings/Precautions

Renal impairment. Monitor blood, renal and hepatic function in long-term use. Avoid sun and UV light. Discontinue if skin erythema occurs. Pregnancy (Cat.D), nursing mothers: not recommended.

Tetracycline Pharmacokinetics

See Literature

Tetracycline Interactions

Interactions

Avoid methoxyflurane, photosensitizing agents. May antagonize bactericidal antibiotics; avoid. Reduced absorption with antacids, iron, zinc, calcium, magnesium, dairy products, urinary alkalinizers, other multivalent cations. May reduce effectiveness of oral contraceptives. Monitor prothrombin time with oral anticoagulants.

Tetracycline Adverse Reactions

Adverse Reactions

Photosensitivity, GI upset, rash, blood dyscrasias, increased BUN, hepatotoxicity; rare: esophagitis and esophageal ulceration.

Tetracycline Clinical Trials

See Literature

Tetracycline Note

Notes

Formerly known under the brand names Achromycin V, Tetracyn, Tetrex.

Tetracycline Patient Counseling

See Literature