Tazorac

— THERAPEUTIC CATEGORIES —
  • Acne
  • Psoriasis

Tazorac Generic Name & Formulations

General Description

Tazarotene 0.05%, 0.1%; gel; crm.

Pharmacological Class

Retinoid.

How Supplied

Gel—30g, 100g; Crm—30g, 60g

Manufacturer

Generic Availability

Gel (YES); Crm 0.1% (YES), 0.05% (NO)

Tazorac Indications

Indications

Mild to moderate facial acne vulgaris (0.1% strength only).

Tazorac Dosage and Administration

Adult

Cleanse and dry skin. Apply thin film of 0.1% strength to lesions on face once daily in the PM. Women of childbearing potential: begin therapy during normal menses.

Children

<12yrs: not established.

Tazorac Contraindications

Contraindications

Pregnancy.

Tazorac Boxed Warnings

Not Applicable

Tazorac Warnings/Precautions

Warnings/Precautions

Embryo-fetal toxicity. Obtain reliable negative pregnancy test within 2wks before starting therapy; use effective contraception during therapy. Do not use on broken, eczematous, or sunburned skin. Sun sensitivity. Avoid eyes, mouth, mucous membranes, sun and UV light; use adequate sun protection. Increased irritation in extreme weather. Discontinue or reduce frequency if excessive irritation occurs. Nursing mothers.

Tazorac Pharmacokinetics

Metabolism

Hepatic. >99% serum protein bound.

Elimination

Renal, fecal. Half-life: ~18 hours.

Tazorac Interactions

Interactions

Avoid use until the effects of strong topical drying agents have subsided. Caution with other photosensitizers or irritants. Separate use of emollients at least 1hr before Tazorac.

Tazorac Adverse Reactions

Adverse Reactions

Desquamation, burning/stinging, dry skin, erythema, pruritus, worsening of psoriasis, irritation, skin pain; photosensitivity.

Tazorac Clinical Trials

See Literature

Tazorac Note

Not Applicable

Tazorac Patient Counseling

See Literature

Tazorac Generic Name & Formulations

General Description

Tazarotene 0.05%, 0.1%; gel; crm.

Pharmacological Class

Retinoid.

How Supplied

Gel—30g, 100g; Crm—30g, 60g

Manufacturer

Generic Availability

Gel (YES); Crm 0.1% (YES), 0.05% (NO)

Tazorac Indications

Indications

Plaque psoriasis.

Tazorac Dosage and Administration

Adult

Cleanse and dry skin. Apply thin film to lesions once daily in the PM; for gel, apply to max 20% body surface area. Initiate with 0.05% strength; may increase to 0.1% as tolerated and clinically indicated. Women of childbearing potential: begin therapy during normal menses.

Children

<18yrs: not established.

Tazorac Contraindications

Contraindications

Pregnancy.

Tazorac Boxed Warnings

Not Applicable

Tazorac Warnings/Precautions

Warnings/Precautions

Embryo-fetal toxicity. Obtain reliable negative pregnancy test within 2wks before starting therapy; use effective contraception during therapy. Do not use on broken, eczematous, or sunburned skin. Sun sensitivity. Avoid eyes, mouth, mucous membranes, sun and UV light; use adequate sun protection. Increased irritation in extreme weather. Discontinue or reduce frequency if excessive irritation occurs. Nursing mothers.

Tazorac Pharmacokinetics

Metabolism

Hepatic. >99% serum protein bound.

Elimination

Renal, fecal. Half-life: ~18 hours.

Tazorac Interactions

Interactions

Avoid use until the effects of strong topical drying agents have subsided. Caution with other photosensitizers or irritants. Separate use of emollients at least 1hr before Tazorac.

Tazorac Adverse Reactions

Adverse Reactions

Desquamation, burning/stinging, dry skin, erythema, pruritus, worsening of psoriasis, irritation, skin pain; photosensitivity.

Tazorac Clinical Trials

See Literature

Tazorac Note

Not Applicable

Tazorac Patient Counseling

See Literature

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