Taclonex Ointment

— THERAPEUTIC CATEGORIES —
  • Psoriasis

Taclonex Ointment Generic Name & Formulations

General Description

Calcipotriene (as hydrate) 0.005% + betamethasone dipropionate 0.064%.

Pharmacological Class

Vit. D3 derivative + topical steroid.

How Supplied

Oint—60g, 100g; Susp—60g, 2x60g

Manufacturer

Generic Availability

NO

Mechanism of Action

Calcipotriene hydrate is a synthetic Vit.D3 analogue. Betamethasone diproprionate is a synthetic corticosteroid. The exact mechanism of action for psoriasis treatment is unknown.

Taclonex Ointment Indications

Indications

Plaque psoriasis.

Taclonex Ointment Dosage and Administration

Adults and Children

<12yrs: not established. Apply to affected areas once daily for up to 4 weeks; discontinue when control is achieved. 12–17yrs: max 60g/wk. ≥18yrs: max 100g/wk. Limit treatment area to max 30% body surface area. Do not occlude.

Administration

Rub ointment in gently and completely. Patients should wash hands after applying. Not for oral, ophthalmic or intravaginal use. Do not use on face, axillae, or groin, or if atrophy is present at treatment site. Do not occlude.

Nursing Considerations

Rub ointment in gently and completely. Patients should wash hands after applying. Not for oral, ophthalmic or intravaginal use. Do not use on face, axillae, or groin, or if atrophy is present at treatment site. Do not occlude.

Taclonex Ointment Contraindications

Not Applicable

Taclonex Ointment Boxed Warnings

Not Applicable

Taclonex Ointment Warnings/Precautions

Warnings/Precautions

Avoid use near eyes, on face, groin, or axillae, or if atrophy is present at treatment site. Discontinue if hypercalcemia or hypercalciuria develop; may resume once calcium metabolism has normalized. Discontinue or reduce dose or potency if HPA axis suppression, Cushing's syndrome, hyperglycemia, or irritation occurs. Increased risk of posterior subcapsular cataracts and glaucoma; monitor for visual symptoms. Avoid sun, UV light (eg, phototherapy). Allergic contact dermatitis. Pregnancy. Nursing mothers.

Taclonex Ointment Pharmacokinetics

See Literature

Taclonex Ointment Interactions

Interactions

Systemic absorption potentiated by other corticosteroids.

Taclonex Ointment Adverse Reactions

Adverse Reactions

Oint: pruritus, scaly rash. Susp: folliculitis, burning sensation of skin.

Taclonex Ointment Clinical Trials

See Literature

Taclonex Ointment Note

Not Applicable

Taclonex Ointment Patient Counseling

See Literature