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Rhofade Generic Name & Formulations
Legal Class
Rx
General Description
Oxymetazoline HCl 1%; crm.
Pharmacological Class
Sympathomimetic.
How Supplied
Gel—30g, 60g (tube or pump)
Manufacturer
Generic Availability
NO
Mechanism of Action
Oxymetazoline is an alpha1A adrenoceptor agonist. Oxymetazoline acts as a vasoconstrictor.
Rhofade Indications
Indications
Persistent facial erythema associated with rosacea.
Rhofade Dosage and Administration
Adult
≥18yrs: apply a pea-sized amount once daily in a thin layer to entire face (forehead, nose, each cheek, chin). Wash hands after use.
Children
<18yrs: not established.
Rhofade Contraindications
Not Applicable
Rhofade Boxed Warnings
Not Applicable
Rhofade Warnings/Precautions
Warnings/Precautions
Not for oral, ophthalmic, or intravaginal use. Avoid eyes, lips, irritated skin, or open wounds. Severe or unstable/uncontrolled cardiovascular disease. Orthostatic hypotension. Uncontrolled hypertension or hypotension. Cerebral or coronary insufficiency. Raynaud's phenomenon. Thromboangiitis obliterans. Scleroderma. Sjögren's syndrome. Increased risk of angle closure glaucoma. Pregnancy. Nursing mothers.
Rhofade Pharmacokinetics
Rhofade Interactions
Interactions
Caution with concomitant beta-blockers, antihypertensives, cardiac glycosides, alpha-1 receptor antagonists. Concomitant MAOIs may affect the metabolism and uptake of circulating amines; caution.
Rhofade Adverse Reactions
Adverse Reactions
Application site reactions (eg, dermatitis, pruritus, erythema, pain), worsening inflammatory lesions of rosacea.
Rhofade Clinical Trials
See Literature
Rhofade Note
Not Applicable
Rhofade Patient Counseling
See Literature
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