Regranex

≥16yrs: Apply once daily until complete healing has occurred. Measure size of ulcer and adjust at 1–2 week intervals. Calculate amount of gel needed based on ulcer size. Length of gel (in cm) to be applied daily = (length x width of wound area in cm²) ÷ 4. Or, length of gel (in inches) to be applied daily = (length x width of wound area in inches²) x 0.6. Squeeze calculated length of gel from tube onto clean measuring surface (eg, wax paper). Spread gel over entire ulcer to thickness of about 1/16 inch. Cover with saline dressing for about 12hrs. Remove dressing and rinse. Replace with clean saline dressing (no gel). Reevaluate if ulcer does not decrease in size by about 30% after 10 weeks, or if complete healing has not occurred after 20 weeks.