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Oxistat Generic Name & Formulations
Legal Class
Rx
General Description
Oxiconazole nitrate 1%; lotion.
Pharmacological Class
Azole antifungal.
How Supplied
Lotion—30mL, 60mL
Manufacturer
Mechanism of Action
Oxiconazole nitrate is an imidazole derivative whose antifungal activity is derived primarily from the inhibition of ergosterol biosynthesis, which is critical for cellular membrane integrity. It has in vitro activity against a wide range of pathogenic fungi.
Oxistat Indications
Indications
Tinea pedis, cruris, and corporis.
Oxistat Dosage and Administration
Adult
Apply 1–2 times daily. Use for 2 weeks for t. corporis, t. cruris; 1 month for t. pedis. Reevaluate if no improvement.
Children
Not established.
Oxistat Contraindications
Not Applicable
Oxistat Boxed Warnings
Not Applicable
Oxistat Warnings/Precautions
Warnings/Precautions
Avoid eyes, nose, mouth, mucous membranes. Discontinue if sensitivity or irritation occurs. Pregnancy. Nursing mothers.
Oxistat Pharmacokinetics
Elimination
Renal.
Oxistat Interactions
Not Applicable
Oxistat Adverse Reactions
Adverse Reactions
Pruritus, burning.
Oxistat Clinical Trials
See Literature
Oxistat Note
Not Applicable
Oxistat Patient Counseling
See Literature
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