Flurandrenolide Ointment

— THERAPEUTIC CATEGORIES —
  • Topical steroids

Flurandrenolide Ointment Generic Name & Formulations

General Description

Flurandrenolide 0.05%.

Pharmacological Class

Corticosteroid.

How Supplied

Oint, lotion—contact supplier; Tape (roll) 3in x 24in, 3in x 80in—1

Mechanism of Action

The mechanism of the anti-inflammatory effect of topical corticosteroids is not completely understood. Corticosteroids with anti-inflammatory activity may stabilize cellular and lysosomal membranes. It is also suggested that the effect on the membranes of lysosomes prevents the release of proteolytic enzymes and, thus, plays a part in reducing inflammation.

Flurandrenolide Ointment Indications

Indications

Corticosteroid-responsive dermatoses.

Flurandrenolide Ointment Dosage and Administration

Adults and Children

Apply thin film to affected areas 2–3 times daily; discontinue when control is achieved. Do not occlude.

Flurandrenolide Ointment Contraindications

Contraindications

Tape: Serum-exuding lesions. Intertrigo.

Flurandrenolide Ointment Boxed Warnings

Not Applicable

Flurandrenolide Ointment Warnings/Precautions

Warnings/Precautions

Avoid use near eyes, on face, groin, or axillae. Do not use for diaper dermatitis or on pre-existing skin atrophy. Avoid tight-fitting diapers or plastic pants. Risk of HPA axis suppression with high-potency steroids, prolonged use, application to large surface area, use of occlusive dressings, altered skin barrier, liver failure, young age; discontinue gradually, or reduce dose or potency if occurs. Treat infection if present; discontinue if infection persists or worsens. Use lowest effective dose and potency (esp. in children). Reevaluate periodically. Pregnancy (Cat.C). Nursing mothers.

Flurandrenolide Ointment Pharmacokinetics

Metabolism

Hepatic.

Elimination

Renal.

Flurandrenolide Ointment Interactions

Not Applicable

Flurandrenolide Ointment Adverse Reactions

Adverse Reactions

Burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, skin maceration, secondary infections, skin atrophy, striae, miliaria; HPA axis suppression (esp. in children).

Flurandrenolide Ointment Clinical Trials

See Literature

Flurandrenolide Ointment Note

Notes

Formerly known under the brand name Cordran.

Flurandrenolide Ointment Patient Counseling

See Literature