Flurandrenolide Lotion Generic Name & Formulations
Legal Class
Rx
General Description
Flurandrenolide 0.05%.
Pharmacological Class
Corticosteroid.
See Also
How Supplied
Oint, lotion—contact supplier; Tape (roll) 3in x 24in, 3in x 80in—1
Manufacturer
Mechanism of Action
The mechanism of the anti-inflammatory effect of topical corticosteroids is not completely understood. Corticosteroids with anti-inflammatory activity may stabilize cellular and lysosomal membranes. It is also suggested that the effect on the membranes of lysosomes prevents the release of proteolytic enzymes and, thus, plays a part in reducing inflammation.
Flurandrenolide Lotion Indications
Indications
Corticosteroid-responsive dermatoses.
Flurandrenolide Lotion Dosage and Administration
Adults and Children
Shake well before use. Rub small amount into affected areas 2–3 times daily; discontinue when control is achieved. Do not occlude.
Flurandrenolide Lotion Contraindications
Contraindications
Tape: Serum-exuding lesions. Intertrigo.
Flurandrenolide Lotion Boxed Warnings
Not Applicable
Flurandrenolide Lotion Warnings/Precautions
Warnings/Precautions
Avoid use near eyes, on face, groin, or axillae. Do not use for diaper dermatitis or on pre-existing skin atrophy. Avoid tight-fitting diapers or plastic pants. Risk of HPA axis suppression with high-potency steroids, prolonged use, application to large surface area, use of occlusive dressings, altered skin barrier, liver failure, young age; discontinue gradually, or reduce dose or potency if occurs. Treat infection if present; discontinue if infection persists or worsens. Use lowest effective dose and potency (esp. in children). Reevaluate periodically. Pregnancy (Cat.C). Nursing mothers.
Flurandrenolide Lotion Pharmacokinetics
Elimination
Renal.
Flurandrenolide Lotion Interactions
Not Applicable
Flurandrenolide Lotion Adverse Reactions
Adverse Reactions
Burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, skin maceration, secondary infections, skin atrophy, striae, miliaria; HPA axis suppression (esp. in children).
Flurandrenolide Lotion Clinical Trials
See Literature
Flurandrenolide Lotion Note
Notes
Formerly known under the brand name Cordran.
Flurandrenolide Lotion Patient Counseling
See Literature