Flurandrenolide Lotion

— THERAPEUTIC CATEGORIES —
  • Topical steroids

Flurandrenolide Lotion Generic Name & Formulations

General Description

Flurandrenolide 0.05%.

Pharmacological Class

Corticosteroid.

How Supplied

Oint, lotion—contact supplier; Tape (roll) 3in x 24in, 3in x 80in—1

Mechanism of Action

The mechanism of the anti-inflammatory effect of topical corticosteroids is not completely understood. Corticosteroids with anti-inflammatory activity may stabilize cellular and lysosomal membranes. It is also suggested that the effect on the membranes of lysosomes prevents the release of proteolytic enzymes and, thus, plays a part in reducing inflammation.

Flurandrenolide Lotion Indications

Indications

Corticosteroid-responsive dermatoses.

Flurandrenolide Lotion Dosage and Administration

Adults and Children

Shake well before use. Rub small amount into affected areas 2–3 times daily; discontinue when control is achieved. Do not occlude.

Flurandrenolide Lotion Contraindications

Contraindications

Tape: Serum-exuding lesions. Intertrigo.

Flurandrenolide Lotion Boxed Warnings

Not Applicable

Flurandrenolide Lotion Warnings/Precautions

Warnings/Precautions

Avoid use near eyes, on face, groin, or axillae. Do not use for diaper dermatitis or on pre-existing skin atrophy. Avoid tight-fitting diapers or plastic pants. Risk of HPA axis suppression with high-potency steroids, prolonged use, application to large surface area, use of occlusive dressings, altered skin barrier, liver failure, young age; discontinue gradually, or reduce dose or potency if occurs. Treat infection if present; discontinue if infection persists or worsens. Use lowest effective dose and potency (esp. in children). Reevaluate periodically. Pregnancy (Cat.C). Nursing mothers.

Flurandrenolide Lotion Pharmacokinetics

Metabolism

Hepatic.

Elimination

Renal.

Flurandrenolide Lotion Interactions

Not Applicable

Flurandrenolide Lotion Adverse Reactions

Adverse Reactions

Burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, skin maceration, secondary infections, skin atrophy, striae, miliaria; HPA axis suppression (esp. in children).

Flurandrenolide Lotion Clinical Trials

See Literature

Flurandrenolide Lotion Note

Notes

Formerly known under the brand name Cordran.

Flurandrenolide Lotion Patient Counseling

See Literature