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Ecoza Generic Name & Formulations
Legal Class
General Description
Pharmacological Class
How Supplied
Canister—1
Manufacturer
Generic Availability
NO
Mechanism of Action
Econazole nitrate inhibits fungal cytochrome P-450-mediated 14 alphalanosterol demethylase enzyme. This enzyme functions to convert lanosterol to ergosterol. The accumulation of 14 alpha-methyl sterols correlates with the subsequent loss of ergosterol in the fungal cell wall and may be responsible for the fungistatic activity of econazole.
Ecoza Indications
Indications
Interdigital tinea pedis caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum.
Ecoza Dosage and Administration
Adult
Apply to affected areas once daily for 4 weeks.
Children
<12yrs: not established.
Administration
For topical use only. Not for oral, ophthalmic, or intravaginal use.
Ecoza Contraindications
Not Applicable
Ecoza Boxed Warnings
Not Applicable
Ecoza Warnings/Precautions
Warnings/Precautions
Avoid heat, flame, smoking during and immediately after application. Flammable. Discontinue if sensitivity or irritation develops. Pregnancy. Nursing mothers.
Ecoza Pharmacokinetics
See Literature
Ecoza Interactions
Interactions
Potentiates warfarin; monitor INR and/or PT (esp. if applied to large body surface areas, genital area, or under occlusion).
Ecoza Adverse Reactions
Adverse Reactions
Application site reactions.
Ecoza Clinical Trials
See Literature
Ecoza Note
Not Applicable
Ecoza Patient Counseling
See Literature
