Share on Facebook
Share on Twitter
Share on LinkedIn
Share by Email
Print
Doxycycline Monohydrate Capsules Generic Name & Formulations
Legal Class
Rx
General Description
Doxycycline monohydrate 50mg, 75mg, 100mg.
Pharmacological Class
Tetracycline antibiotic.
How Supplied
Contact supplier
Manufacturer
Doxycycline Monohydrate Capsules Indications
Indications
Adjunct in severe acne.
Doxycycline Monohydrate Capsules Dosage and Administration
Adult
Take with fluids; may give with food or milk if gastric irritation occurs. 200mg for 1 day (100mg every 12hrs or 50mg every 6hrs), then 100mg daily (as a single dose or 50mg every 12hrs).
Children
≤8yrs: not usually recommended. Take with fluids; may give with food or milk if gastric irritation occurs. >8yrs (<45kg): 4.4mg/kg in 2 divided doses for 1 day, then 2.2mg/kg daily (as a single dose or divided as 2 doses); (≥45kg): use Adults dose.
Doxycycline Monohydrate Capsules Contraindications
Not Applicable
Doxycycline Monohydrate Capsules Boxed Warnings
Not Applicable
Doxycycline Monohydrate Capsules Warnings/Precautions
Warnings/Precautions
Monitor blood, renal, and hepatic function in long-term use. Discontinue if skin erythema or superinfection develops. Avoid sun or UV light. Overweight women. History of intracranial hypertension. Monitor for visual disturbances. Pregnancy (Cat.D), nursing mothers: not recommended.
Doxycycline Monohydrate Capsules Pharmacokinetics
See Literature
Doxycycline Monohydrate Capsules Interactions
Interactions
Avoid concomitant penicillins, isotretinoin. Fatal renal toxicity with concomitant methoxyflurane. May need to reduce concomitant anticoagulant dose. Absorption reduced by antacids containing aluminum, calcium, magnesium and iron. May be antagonized by barbiturates, carbamazepine, phenytoin. May antagonize oral contraceptives. May interfere with fluorescence test.
Doxycycline Monohydrate Capsules Adverse Reactions
Adverse Reactions
Anorexia, nausea, vomiting, diarrhea, rash, photosensitivity, urticaria, hemolytic anemia; teeth discoloration, delayed skeletal development, intracranial hypertension, C.difficile-associated diarrhea.
Doxycycline Monohydrate Capsules Clinical Trials
See Literature
Doxycycline Monohydrate Capsules Note
Notes
Formerly known under the brand name Monodox.
Doxycycline Monohydrate Capsules Patient Counseling
See Literature
Doxycycline Monohydrate Capsules Generic Name & Formulations
Legal Class
Rx
General Description
Doxycycline monohydrate 50mg, 75mg, 100mg.
Pharmacological Class
Tetracycline antibiotic.
How Supplied
Contact supplier
Manufacturer
Doxycycline Monohydrate Capsules Indications
Indications
Tetracycline-susceptible infections including respiratory, genitourinary, rickettsial, trachoma. Alternative for selected infections when penicillin is contraindicated. Anthrax, including inhalational anthrax (postexposure).
Doxycycline Monohydrate Capsules Dosage and Administration
Adult
Take with fluids; may give with food or milk if gastric irritation occurs. 200mg for 1 day (100mg every 12hrs or 50mg every 6hrs), then 100mg daily (as a single dose or 50mg every 12hrs); if severe infections (eg, chronic UTI): 100mg every 12 hours. Streptococcal infections: treat for 10 days. Uncomplicated urethral, endocervical, rectal infection, or nongonococcal urethritis (NGU): 100mg twice daily for 7 days. Uncomplicated gonococcal infections (except anorectal infections in men): 100mg twice daily for 7 days or 300mg single dose followed by a second 300mg dose 1hr later. Acute epididymo-orchitis: 100mg twice daily for at least 10 days. Syphilis (primary/secondary): 300mg/day in divided doses for at least 10 days. Anthrax: 100mg twice daily for 60 days.
Children
≤8yrs: not usually recommended. Take with fluids; may give with food or milk if gastric irritation occurs. >8yrs (<45kg): 4.4mg/kg in 2 divided doses for 1 day, then 2.2mg/kg daily (as a single dose or divided as 2 doses); if severe infections: 2.2mg/kg every 12hrs; (≥45kg): use Adults dose. Anthrax (<45kg): 2.2mg/kg twice daily for 60 days; (≥45kg): use Adults dose.
Doxycycline Monohydrate Capsules Contraindications
Not Applicable
Doxycycline Monohydrate Capsules Boxed Warnings
Not Applicable
Doxycycline Monohydrate Capsules Warnings/Precautions
Warnings/Precautions
Monitor blood, renal, and hepatic function in long-term use. Discontinue if skin erythema or superinfection develops. Avoid sun or UV light. Overweight women. History of intracranial hypertension. Monitor for visual disturbances. Pregnancy (Cat.D), nursing mothers: not recommended.
Doxycycline Monohydrate Capsules Pharmacokinetics
See Literature
Doxycycline Monohydrate Capsules Interactions
Interactions
Avoid concomitant penicillins, isotretinoin. Fatal renal toxicity with concomitant methoxyflurane. May need to reduce concomitant anticoagulant dose. Absorption reduced by antacids containing aluminum, calcium, magnesium and iron. May be antagonized by barbiturates, carbamazepine, phenytoin. May antagonize oral contraceptives. May interfere with fluorescence test.
Doxycycline Monohydrate Capsules Adverse Reactions
Adverse Reactions
Anorexia, nausea, vomiting, diarrhea, rash, photosensitivity, urticaria, hemolytic anemia; teeth discoloration, delayed skeletal development, intracranial hypertension, C.difficile-associated diarrhea.
Doxycycline Monohydrate Capsules Clinical Trials
See Literature
Doxycycline Monohydrate Capsules Note
Notes
See MMWR Vol 50, No.42 (Oct. 26, 2001) for more information on anthrax.
Doxycycline Monohydrate Capsules Patient Counseling
See Literature
Doxycycline Monohydrate Capsules Generic Name & Formulations
Legal Class
Rx
General Description
Doxycycline monohydrate 50mg, 75mg, 100mg.
Pharmacological Class
Tetracycline antibiotic.
How Supplied
Contact supplier
Manufacturer
Doxycycline Monohydrate Capsules Indications
Indications
Adjunct in acute intestinal amebiasis.
Doxycycline Monohydrate Capsules Dosage and Administration
Adult
Take with fluids; may give with food or milk if gastric irritation occurs. 200mg for 1 day (100mg every 12hrs or 50mg every 6hrs), then 100mg daily (as a single dose or 50mg every 12hrs); if severe infections: 100mg every 12hrs.
Children
≤8yrs: not usually recommended. Take with fluids; may give with food or milk if gastric irritation occurs. >8yrs (<45kg): 4.4mg/kg in 2 divided doses for 1 day, then 2.2mg/kg daily (as a single dose or divided as 2 doses); if severe infections: 2.2mg/kg every 12hrs; (≥45kg): use Adults dose.
Doxycycline Monohydrate Capsules Contraindications
Not Applicable
Doxycycline Monohydrate Capsules Boxed Warnings
Not Applicable
Doxycycline Monohydrate Capsules Warnings/Precautions
Warnings/Precautions
Monitor blood, renal, and hepatic function in long-term use. Discontinue if skin erythema or superinfection develops. Avoid sun or UV light. Overweight women. History of intracranial hypertension. Monitor for visual disturbances. Pregnancy (Cat.D), nursing mothers: not recommended.
Doxycycline Monohydrate Capsules Pharmacokinetics
See Literature
Doxycycline Monohydrate Capsules Interactions
Interactions
Avoid concomitant penicillins, isotretinoin. Fatal renal toxicity with concomitant methoxyflurane. May need to reduce concomitant anticoagulant dose. Absorption reduced by antacids containing aluminum, calcium, magnesium and iron. May be antagonized by barbiturates, carbamazepine, phenytoin. May antagonize oral contraceptives. May interfere with fluorescence test.
Doxycycline Monohydrate Capsules Adverse Reactions
Adverse Reactions
Anorexia, nausea, vomiting, diarrhea, rash, photosensitivity, urticaria, hemolytic anemia; teeth discoloration, delayed skeletal development, intracranial hypertension, C.difficile-associated diarrhea.
Doxycycline Monohydrate Capsules Clinical Trials
See Literature
Doxycycline Monohydrate Capsules Note
Notes
Formerly known under the brand name Monodox.
Doxycycline Monohydrate Capsules Patient Counseling
See Literature
