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Diprolene Generic Name & Formulations
Legal Class
Rx
General Description
Betamethasone, augmented (as dipropionate) 0.05%; oint.
Pharmacological Class
Corticosteroid.
How Supplied
Oint—15g, 50g
Manufacturer
Diprolene Indications
Indications
Corticosteroid-responsive dermatoses.
Diprolene Dosage and Administration
Adult
≥13yrs: apply thin film 1–2 times daily; max 50g/week. Lotion: apply a few drops 1–2 times daily; max 50mL/week; max 2 consecutive weeks' treatment per course. Discontinue when control is achieved. Do not occlude.
Children
<13yrs: not recommended.
Diprolene Contraindications
Not Applicable
Diprolene Boxed Warnings
Not Applicable
Diprolene Warnings/Precautions
Warnings/Precautions
Avoid use near eyes, on face, groin, or axillae. Do not use for diaper dermatitis or on pre-existing skin atrophy. Risk of HPA axis suppression with high-potency steroids, prolonged use, application to large surface area, use of occlusive dressings, altered skin barrier, liver failure, young age; discontinue gradually, or reduce dose or potency if occurs. Increased risk of posterior subcapsular cataracts and glaucoma; monitor for visual symptoms. Use lowest effective dose and potency (esp. in children). Reevaluate periodically. Pregnancy. Nursing mothers.
Diprolene Pharmacokinetics
See Literature
Diprolene Interactions
Not Applicable
Diprolene Adverse Reactions
Adverse Reactions
Erythema, folliculitis, pruritus, vesiculation; contact dermatitis (discontinue if irritation occurs), HPA axis suppression (esp. in children); rare: Cushing's syndrome, hyperglycemia. Also for AF crm: stinging, skin atrophy, telangiectasia, bruising, shininess.
Diprolene Clinical Trials
See Literature
Diprolene Note
Not Applicable
Diprolene Patient Counseling
See Literature
