Clobex Spray Generic Name & Formulations
Legal Class
Rx
General Description
Clobetasol propionate 0.05%.
See Also
How Supplied
Lotion—2oz, 4oz; Shampoo—4oz; Spray—2oz, 4.25oz
Manufacturer
Clobex Spray Indications
Indications
Moderate-to-severe plaque psoriasis.
Clobex Spray Dosage and Administration
Adult
≥18yrs: Spray on twice daily (AM & PM), rub in gently and completely; max 50g/week and up to 4 consecutive weeks' treatment per course. May use on up to 20% BSA.
Children
<18yrs: not recommended.
Clobex Spray Contraindications
Contraindications
Do not use superpotent forms on face, groin, or axillae. Exclude viral disease (eg, chickenpox, measles).
Clobex Spray Boxed Warnings
Not Applicable
Clobex Spray Warnings/Precautions
Warnings/Precautions
Treat infection if present; discontinue if infection persists or worsens. Avoid contact with eyes, or on diaper dermatitis or pre-existing skin atrophy. Do not use fluorinated steroids longer than 1 week on the face. Avoid abrupt cessation in chronic use. Systemic absorption increased by broken or inflamed skin, prolonged use, application to large surface area, or use of occlusive dressings. Occlude only if necessary; do not occlude higher potency products. Monitor adrenal function in children if a high potency product or occlusion is used, and in adults if more than 50g weekly of a high potency product is used. Increased risks of glaucoma, posterior subcapsular cataract. Discontinue or reduce dose or potency if HPA axis suppression, Cushing's syndrome, hyperglycemia, glucosuria, or irritation occurs. Use lowest effective dose and potency (esp. in children). Use caution if applying to face or body folds. Do not use continuously or for prophylaxis. Foams are flammable. Reevaluate periodically. Pregnancy. Nursing mothers.
Clobex Spray Pharmacokinetics
See Literature
Clobex Spray Interactions
Not Applicable
Clobex Spray Adverse Reactions
Adverse Reactions
Burning, stinging, pruritus, erythema, skin atrophy, striae, miliaria, secondary infections, hypopigmentation, folliculitis, hypertrichosis, acneiform eruptions, dermal cracking and fissuring, telangiectasia, contact dermatitis, other local effects, immunosuppression, masks infections, visual symptoms, HPA axis suppression (esp. in children).
Clobex Spray Clinical Trials
See Literature
Clobex Spray Note
Not Applicable
Clobex Spray Patient Counseling
See Literature
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