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Carac Generic Name & Formulations
Legal Class
Rx
General Description
Fluorouracil 0.5% (0.35% in microspheres); crm.
Pharmacological Class
Antimetabolite.
How Supplied
Crm—30g
Manufacturer
Generic Availability
NO
Carac Indications
Indications
Multiple actinic or solar keratoses of the face and anterior scalp.
Carac Dosage and Administration
Adult
≥18yrs: Wash and dry area. Wait 10mins. Apply thin film to skin where lesions appear once daily for up to 4weeks. Do not occlude. May apply sunscreen/ moisturizer 2hrs later. Wash hands after use.
Children
<18yrs: not established.
Carac Contraindications
Contraindications
Dihydropyrimidine dehydrogenase (DPD) deficiency. Women of childbearing potential. Pregnancy.
Carac Boxed Warnings
Not Applicable
Carac Warnings/Precautions
Warnings/Precautions
Discontinue if symptoms of DPD deficiency develop (eg, abdominal pain, bloody diarrhea, vomiting, fever, chills). Ulcerated or inflamed skin. Avoid eyes, mucous membranes, exposure to sun or UV light. Nursing mothers: not recommended.
Carac Pharmacokinetics
See Literature
Carac Interactions
Not Applicable
Carac Adverse Reactions
Adverse Reactions
Application site reaction (may persist 2 weeks after drug is stopped), eye irritation.
Carac Clinical Trials
See Literature
Carac Note
Not Applicable
Carac Patient Counseling
See Literature
