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Trandate Generic Name & Formulations
Legal Class
Rx
General Description
Labetalol HCl 100mg, 200mg; scored tabs.
Pharmacological Class
Noncardioselective beta-blocker/alpha-1 blocker.
How Supplied
Tabs—100, 500
Manufacturer
Trandate Indications
Indications
Hypertension.
Trandate Dosage and Administration
Adult
Initially 100mg twice a day. Titrate at 2–3 day intervals in increments of 100mg twice daily. Usual maintenance: 200–400mg twice daily; max 2.4g/day.
Children
Not recommended.
Trandate Contraindications
Contraindications
Asthma. 2nd- or 3rd-degree AV block. Overt cardiac failure. Cardiogenic shock. Severe bradycardia, other conditions associated with prolonged or severe hypotension.
Trandate Boxed Warnings
Not Applicable
Trandate Warnings/Precautions
Warnings/Precautions
Ischemic heart disease or failure. Monitor hepatic function; discontinue at first sign of liver injury. COPD. Pheochromocytoma. Diabetes. Surgery. Avoid abrupt cessation. Elderly. Pregnancy (Cat.C). Nursing mothers.
Trandate Pharmacokinetics
See Literature
Trandate Interactions
Interactions
Caution with verapamil. Potentiates hypotension with nitroglycerin. May block epinephrine, β-agonist bronchodilators. Adjust antidiabetic medication. Potentiated by cimetidine. Tremor with tricyclic antidepressants. Halothane.
Trandate Adverse Reactions
Adverse Reactions
Dizziness, GI upset, fatigue, nasal stuffiness, ejaculation failure, headache, dyspnea, vertigo, rash, orthostatic hypotension, edema, heart failure, bronchospasm, jaundice.
Trandate Clinical Trials
See Literature
Trandate Note
Not Applicable
Trandate Patient Counseling
See Literature
