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Quinidine Sulfate Generic Name & Formulations
Legal Class
Rx
General Description
Quinidine sulfate 300mg; ext-rel tabs.
Pharmacological Class
Class I antiarrhythmic.
How Supplied
Contact supplier.
Manufacturer
Quinidine Sulfate Indications
Indications
Atrial and ventricular arrhythmias (see full labeling).
Quinidine Sulfate Dosage and Administration
Adult
Take with food and in an upright position. 300–600mg every 8–12hrs.
Children
Not recommended.
Quinidine Sulfate Contraindications
Contraindications
Complete AV or bundle branch block or other severe intraventricular conduction defects. Myasthenia gravis. Arrhythmias due to digitalis intoxication. Aberrant impulses, abnormal rhythms due to escape mechanisms.
Quinidine Sulfate Boxed Warnings
Not Applicable
Quinidine Sulfate Warnings/Precautions
Warnings/Precautions
Atrial flutter; digitalize first. Incomplete AV block. Marginally compensated cardiovascular disease. Heart failure. Hypotension. Renal or hepatic dysfunction. Monitor blood, liver and kidney function in long-term use. Monitor ECG and serum levels if dose is over 2.5g/day. Pregnancy (Cat.C). Nursing mothers.
Quinidine Sulfate Pharmacokinetics
See Literature
Quinidine Sulfate Interactions
Interactions
Toxicity increased by amiodarone, cimetidine, ranitidine, diuretics, carbonic anhydrase inhibitors, sodium bicarbonate, verapamil, diltiazem. Potentiates anticoagulants, anticholinergics, neuromuscular blocking agents, phenothiazines, reserpine, timolol. Increases digitalis serum levels. Plasma levels decreased by barbiturates, hydantoins, rifampin, nifedipine.
Quinidine Sulfate Adverse Reactions
Adverse Reactions
Nausea, vomiting, abdominal pain, diarrhea, new or exacerbated arrhythmias, heart block, syncope, cinchonism, headache, blood dyscrasias, hypotension, flushing, impaired hearing and vision, allergic reactions, hepatic dysfunction.
Quinidine Sulfate Clinical Trials
See Literature
Quinidine Sulfate Note
Notes
Formerly known under the brand names Cin-quin, Quinidex, Quinora.
Quinidine Sulfate Patient Counseling
See Literature
