Phenylephrine Hcl Injection Generic Name & Formulations
Legal Class
Rx
General Description
Phenylephrine HCl 10mg/mL; soln for IV, IM, or SC inj; contains sulfites.
Pharmacological Class
Sympathomimetic.
How Supplied
Vial 10mg/mL (1mL, 5mL)—25
Manufacturer
Phenylephrine Hcl Injection Indications
Indications
Prolongation of spinal anesthesia. Vasoconstrictor in regional analgesia.
Phenylephrine Hcl Injection Dosage and Administration
Adult
Prolongation of spinal anesthesia: add 2–5mg into anesthetic solution. Vasoconstrictor for regional analgesia: add 1mg to every 20mL (1:20,000) of local anesthetic solution.
Children
Not recommended.
Phenylephrine Hcl Injection Contraindications
Contraindications
Severe hypertension. Ventricular tachycardia.
Phenylephrine Hcl Injection Boxed Warnings
Not Applicable
Phenylephrine Hcl Injection Warnings/Precautions
Warnings/Precautions
Cardiovascular disease. Hypertension. Thyroid disease. Asthma. Sulfite sensitivity. Elderly. Pregnancy (Cat.C). Labor & delivery. Nursing mothers.
Phenylephrine Hcl Injection Pharmacokinetics
See Literature
Phenylephrine Hcl Injection Interactions
Interactions
Potentiated by oxytocic drugs, tricyclic antidepressants, or MAOIs. Caution with halothane anesthesia.
Phenylephrine Hcl Injection Adverse Reactions
Adverse Reactions
Headache, reflex bradycardia, excitability, restlessness: rare: arrhythmias.
Phenylephrine Hcl Injection Clinical Trials
See Literature
Phenylephrine Hcl Injection Note
Not Applicable
Phenylephrine Hcl Injection Patient Counseling
See Literature
Phenylephrine Hcl Injection Generic Name & Formulations
Legal Class
Rx
General Description
Phenylephrine HCl 10mg/mL; soln for IV, IM, or SC inj; contains sulfites.
Pharmacological Class
Sympathomimetic.
How Supplied
Vial 10mg/mL (1mL, 5mL)—25
Manufacturer
Phenylephrine Hcl Injection Indications
Indications
Paroxysmal supraventricular tachycardia.
Phenylephrine Hcl Injection Dosage and Administration
Adult
Give by rapid IV inj within 20–30secs. Initial max dose: 0.5mg, subsequent doses not to exceed preceding dose by 0.1–0.2mg; max: 1mg.
Children
Not recommended.
Phenylephrine Hcl Injection Contraindications
Contraindications
Severe hypertension. Ventricular tachycardia.
Phenylephrine Hcl Injection Boxed Warnings
Not Applicable
Phenylephrine Hcl Injection Warnings/Precautions
Warnings/Precautions
Cardiovascular disease. Hypertension. Thyroid disease. Asthma. Sulfite sensitivity. Elderly. Pregnancy (Cat.C). Labor & delivery. Nursing mothers.
Phenylephrine Hcl Injection Pharmacokinetics
See Literature
Phenylephrine Hcl Injection Interactions
Interactions
Potentiated by oxytocic drugs, tricyclic antidepressants, or MAOIs. Caution with halothane anesthesia.
Phenylephrine Hcl Injection Adverse Reactions
Adverse Reactions
Headache, reflex bradycardia, excitability, restlessness: rare: arrhythmias.
Phenylephrine Hcl Injection Clinical Trials
See Literature
Phenylephrine Hcl Injection Note
Not Applicable
Phenylephrine Hcl Injection Patient Counseling
See Literature
Phenylephrine Hcl Injection Generic Name & Formulations
Legal Class
Rx
General Description
Phenylephrine HCl 10mg/mL; soln for IV, IM, or SC inj; contains sulfites.
Pharmacological Class
Sympathomimetic.
How Supplied
Vial 10mg/mL (1mL, 5mL)—25
Manufacturer
Phenylephrine Hcl Injection Indications
Indications
To maintain adequate blood pressure during spinal and inhalation anesthesia. Vascular failure in shock, shock-like states and drug-induced hypotension or hypersensitivity.
Phenylephrine Hcl Injection Dosage and Administration
Adult
Spinal anesthesia hypotension: treatment or prophylaxis: 2–3mg SC or IM 3–4 minutes prior to spinal anesthesia; hypotensive crisis: initially 0.2mg by IV inj, subsequent doses not to exceed preceding dose by 0.1–0.2mg; max: 0.5mg/dose. Mild or moderate hypotension: SC or IM: usually 2–5mg; initial max dose: 5mg. Range: 1–10mg; IV: usually 0.2mg; initial max dose: 0.5mg. Range: 0.1–0.5mg. Do not repeat injections more often than every 10–15mins. Shock and drug-induced: initially 10mg by continuous IV infusion, if non-responsive, add additional 10mg (or more) into infusion bottle. See literature.
Children
Spinal anesthesia hypotension: 0.5–1mg/25lbs body weight by SC or IM.
Phenylephrine Hcl Injection Contraindications
Contraindications
Severe hypertension. Ventricular tachycardia.
Phenylephrine Hcl Injection Boxed Warnings
Not Applicable
Phenylephrine Hcl Injection Warnings/Precautions
Warnings/Precautions
Cardiovascular disease. Hypertension. Thyroid disease. Asthma. Sulfite sensitivity. Elderly. Pregnancy (Cat.C). Labor & delivery. Nursing mothers.
Phenylephrine Hcl Injection Pharmacokinetics
See Literature
Phenylephrine Hcl Injection Interactions
Interactions
Potentiated by oxytocic drugs, tricyclic antidepressants, or MAOIs. Caution with halothane anesthesia.
Phenylephrine Hcl Injection Adverse Reactions
Adverse Reactions
Headache, reflex bradycardia, excitability, restlessness: rare: arrhythmias.
Phenylephrine Hcl Injection Clinical Trials
See Literature
Phenylephrine Hcl Injection Note
Not Applicable
Phenylephrine Hcl Injection Patient Counseling
See Literature