Phenylephrine Hcl Injection

— THERAPEUTIC CATEGORIES —
  • Anesthetics
  • CHF and arrhythmias
  • Hypotension

Phenylephrine Hcl Injection Generic Name & Formulations

General Description

Phenylephrine HCl 10mg/mL; soln for IV, IM, or SC inj; contains sulfites.

Pharmacological Class

Sympathomimetic.

How Supplied

Vial 10mg/mL (1mL, 5mL)—25

Manufacturer

Phenylephrine Hcl Injection Indications

Indications

Prolongation of spinal anesthesia. Vasoconstrictor in regional analgesia.

Phenylephrine Hcl Injection Dosage and Administration

Adult

Prolongation of spinal anesthesia: add 2–5mg into anesthetic solution. Vasoconstrictor for regional analgesia: add 1mg to every 20mL (1:20,000) of local anesthetic solution.

Children

Not recommended.

Phenylephrine Hcl Injection Contraindications

Contraindications

Severe hypertension. Ventricular tachycardia.

Phenylephrine Hcl Injection Boxed Warnings

Not Applicable

Phenylephrine Hcl Injection Warnings/Precautions

Warnings/Precautions

Cardiovascular disease. Hypertension. Thyroid disease. Asthma. Sulfite sensitivity. Elderly. Pregnancy (Cat.C). Labor & delivery. Nursing mothers.

Phenylephrine Hcl Injection Pharmacokinetics

See Literature

Phenylephrine Hcl Injection Interactions

Interactions

Potentiated by oxytocic drugs, tricyclic antidepressants, or MAOIs. Caution with halothane anesthesia.

Phenylephrine Hcl Injection Adverse Reactions

Adverse Reactions

Headache, reflex bradycardia, excitability, restlessness: rare: arrhythmias.

Phenylephrine Hcl Injection Clinical Trials

See Literature

Phenylephrine Hcl Injection Note

Not Applicable

Phenylephrine Hcl Injection Patient Counseling

See Literature

Phenylephrine Hcl Injection Generic Name & Formulations

General Description

Phenylephrine HCl 10mg/mL; soln for IV, IM, or SC inj; contains sulfites.

Pharmacological Class

Sympathomimetic.

How Supplied

Vial 10mg/mL (1mL, 5mL)—25

Manufacturer

Phenylephrine Hcl Injection Indications

Indications

Paroxysmal supraventricular tachycardia.

Phenylephrine Hcl Injection Dosage and Administration

Adult

Give by rapid IV inj within 20–30secs. Initial max dose: 0.5mg, subsequent doses not to exceed preceding dose by 0.1–0.2mg; max: 1mg.

Children

Not recommended.

Phenylephrine Hcl Injection Contraindications

Contraindications

Severe hypertension. Ventricular tachycardia.

Phenylephrine Hcl Injection Boxed Warnings

Not Applicable

Phenylephrine Hcl Injection Warnings/Precautions

Warnings/Precautions

Cardiovascular disease. Hypertension. Thyroid disease. Asthma. Sulfite sensitivity. Elderly. Pregnancy (Cat.C). Labor & delivery. Nursing mothers.

Phenylephrine Hcl Injection Pharmacokinetics

See Literature

Phenylephrine Hcl Injection Interactions

Interactions

Potentiated by oxytocic drugs, tricyclic antidepressants, or MAOIs. Caution with halothane anesthesia.

Phenylephrine Hcl Injection Adverse Reactions

Adverse Reactions

Headache, reflex bradycardia, excitability, restlessness: rare: arrhythmias.

Phenylephrine Hcl Injection Clinical Trials

See Literature

Phenylephrine Hcl Injection Note

Not Applicable

Phenylephrine Hcl Injection Patient Counseling

See Literature

Phenylephrine Hcl Injection Generic Name & Formulations

General Description

Phenylephrine HCl 10mg/mL; soln for IV, IM, or SC inj; contains sulfites.

Pharmacological Class

Sympathomimetic.

How Supplied

Vial 10mg/mL (1mL, 5mL)—25

Manufacturer

Phenylephrine Hcl Injection Indications

Indications

To maintain adequate blood pressure during spinal and inhalation anesthesia. Vascular failure in shock, shock-like states and drug-induced hypotension or hypersensitivity.

Phenylephrine Hcl Injection Dosage and Administration

Adult

Spinal anesthesia hypotension: treatment or prophylaxis: 2–3mg SC or IM 3–4 minutes prior to spinal anesthesia; hypotensive crisis: initially 0.2mg by IV inj, subsequent doses not to exceed preceding dose by 0.1–0.2mg; max: 0.5mg/dose. Mild or moderate hypotension: SC or IM: usually 2–5mg; initial max dose: 5mg. Range: 1–10mg; IV: usually 0.2mg; initial max dose: 0.5mg. Range: 0.1–0.5mg. Do not repeat injections more often than every 10–15mins. Shock and drug-induced: initially 10mg by continuous IV infusion, if non-responsive, add additional 10mg (or more) into infusion bottle. See literature.

Children

Spinal anesthesia hypotension: 0.5–1mg/25lbs body weight by SC or IM.

Phenylephrine Hcl Injection Contraindications

Contraindications

Severe hypertension. Ventricular tachycardia.

Phenylephrine Hcl Injection Boxed Warnings

Not Applicable

Phenylephrine Hcl Injection Warnings/Precautions

Warnings/Precautions

Cardiovascular disease. Hypertension. Thyroid disease. Asthma. Sulfite sensitivity. Elderly. Pregnancy (Cat.C). Labor & delivery. Nursing mothers.

Phenylephrine Hcl Injection Pharmacokinetics

See Literature

Phenylephrine Hcl Injection Interactions

Interactions

Potentiated by oxytocic drugs, tricyclic antidepressants, or MAOIs. Caution with halothane anesthesia.

Phenylephrine Hcl Injection Adverse Reactions

Adverse Reactions

Headache, reflex bradycardia, excitability, restlessness: rare: arrhythmias.

Phenylephrine Hcl Injection Clinical Trials

See Literature

Phenylephrine Hcl Injection Note

Not Applicable

Phenylephrine Hcl Injection Patient Counseling

See Literature