Phentolamine Generic Name & Formulations
Legal Class
Rx
General Description
Phentolamine mesylate 5mg/vial; for IM or IV inj after reconstitution; contains mannitol.
Pharmacological Class
Alpha adrenergic blocker.
How Supplied
Vial—1
Manufacturer
Phentolamine Indications
Indications
Hypertensive episodes in patients with pheochromocytoma.
Phentolamine Dosage and Administration
Adult
Pre-op: 5mg IV or IM 1–2 hrs before surgery; may repeat. During surgery: 5mg IV as needed. See literature.
Children
Pre-op: 1mg IV or IM 1–2 hrs before surgery; may repeat. During surgery: 1mg IV as needed. See literature.
Phentolamine Contraindications
Contraindications
MI or history of MI. Coronary insufficiency. Angina. Coronary artery disease.
Phentolamine Boxed Warnings
Not Applicable
Phentolamine Warnings/Precautions
Warnings/Precautions
Arrhythmias. Pregnancy (Cat.C). Nursing mothers: not recommended.
Phentolamine Pharmacokinetics
See Literature
Phentolamine Interactions
Interactions
Avoid concomitant cardiac glycosides.
Phentolamine Adverse Reactions
Adverse Reactions
Cerebrovascular spasms or occlusion, MI, tachycardia, arrhythmias, hypotension, weakness, dizziness, flushing, nasal congestion, GI disturbances.
Phentolamine Clinical Trials
See Literature
Phentolamine Note
Notes
Formerly known under the brand name Regitine.
Phentolamine Patient Counseling
See Literature