Persantine

— THERAPEUTIC CATEGORIES —
  • Thromboembolic disorders

Persantine Generic Name & Formulations

General Description

Dipyridamole 25mg, 50mg, 75mg; tabs.

Pharmacological Class

Antiplatelet.

How Supplied

Tabs—100

Persantine Indications

Indications

Adjunct to oral anticoagulants after cardiac valve replacement to prevent thromboembolism.

Persantine Dosage and Administration

Adult

75mg–100mg four times a day.

Children

Not established.

Persantine Contraindications

Not Applicable

Persantine Boxed Warnings

Not Applicable

Persantine Warnings/Precautions

Warnings/Precautions

Severe coronary artery disease (eg, unstable angina, recent MI). Hypotension. Potential hepatic insufficiency. Interrupt dose for 48hrs prior to stress testing (w. IV dipyridamole, other adenosinergic agents). Pregnancy. Nursing mothers.

Persantine Pharmacokinetics

See Literature

Persantine Interactions

Interactions

May potentiate cardiovascular effects of IV adenosinergic agents (eg, adenosine, regadenoson). May antagonize cholinesterase inhibitors.

Persantine Adverse Reactions

Adverse Reactions

Dizziness, abdominal distress, headache, rash.

Persantine Clinical Trials

See Literature

Persantine Note

Not Applicable

Persantine Patient Counseling

See Literature