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Nitrostat Generic Name & Formulations
Legal Class
Rx
General Description
Nitroglycerin 0.3mg, 0.4mg, 0.6mg; sublingual tabs.
Pharmacological Class
Nitrate.
How Supplied
Tabs 0.4mg—4 x 25, 100; 0.3mg, 0.6mg—100
Manufacturer
Nitrostat Indications
Indications
Acute relief of angina attack. Acute prophylaxis of angina pectoris.
Nitrostat Dosage and Administration
Adult
Use lowest effective dose. Treatment: 1 tab sublingually or in buccal pouch at onset, may repeat in 5mins; max 3 tabs in 15mins. Prophylaxis: 5–10mins before activity.
Children
Not established.
Nitrostat Contraindications
Contraindications
Severe anemia. Increased intracranial pressure (eg, cerebral hemorrhage, traumatic brain injury). Acute circulatory failure or shock. Concomitant PDE-5 inhibitors (eg, avanafil, sildenafil, tadalafil, vardenafil), soluble guanylate cyclase stimulators (eg, riociguat).
Nitrostat Boxed Warnings
Not Applicable
Nitrostat Warnings/Precautions
Warnings/Precautions
Constrictive pericarditis, aortic or mitral stenosis, volume-depleted, hypotensive: increased risk of severe hypotension. Hypertrophic cardiomyopathy. Elderly. Pregnancy. Nursing mothers: not studied.
Nitrostat Pharmacokinetics
See Literature
Nitrostat Interactions
Interactions
See Contraindications. Hypotension potentiated by PDE-5 inhibitors, riociguat. Avoid ergotamine and related drugs.
Nitrostat Adverse Reactions
Adverse Reactions
Headache, dizziness, paresthesia, vertigo, weakness, palpitation, postural hypotension, syncope, flushing, rash, exfoliative dermatitis.
Nitrostat Clinical Trials
See Literature
Nitrostat Note
Not Applicable
Nitrostat Patient Counseling
See Literature
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