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Nexiclon Xr Generic Name & Formulations
Legal Class
Rx
General Description
Clonidine 0.17mg, 0.26mg; ext-rel tabs; scored.
Pharmacological Class
Central alpha-2 agonist.
How Supplied
Tabs—90
Manufacturer
Generic Availability
NO
Nexiclon Xr Indications
Indications
Hypertension.
Nexiclon Xr Dosage and Administration
Adult
Individualize. Initially 0.17mg once daily at bedtime; may titrate by 0.09mg once daily in weekly increments if needed until desired response. Usual range: 0.17–0.52mg/day. Elderly: may benefit from a lower initial dose. ESRD on maintenance dialysis: initially 0.09mg/day and up-titrate slowly to minimize adverse events; monitor closely.
Children
Not established.
Nexiclon Xr Contraindications
Not Applicable
Nexiclon Xr Boxed Warnings
Not Applicable
Nexiclon Xr Warnings/Precautions
Warnings/Precautions
Avoid abrupt cessation. Reduce dose gradually over 2–4 days to avoid withdrawal symptoms. Severe coronary insufficiency, conduction disturbances, recent MI, cerebrovascular disease, or chronic renal failure; monitor closely and up-titrate slowly. May be administered up to 28 hours prior to surgery and resumed the following day. If local contact sensitization or allergic reaction occurs from patch, using tabs may cause generalized rash or an allergic reaction. Renal impairment. Elderly. Pregnancy (Cat.C). Nursing mothers.
Nexiclon Xr Pharmacokinetics
See Literature
Nexiclon Xr Interactions
Interactions
May increase sedative effect with concomitant use of alcohol, barbiturates, or other sedating drugs. Antagonized by tricyclic antidepressants. Monitor heart rate in patients receiving agents known to affect sinus node function or AV nodal conduction (eg, digitalis, calcium channel blockers, β-blockers).
Nexiclon Xr Adverse Reactions
Adverse Reactions
Dry mouth, drowsiness, dizziness, constipation, sedation.
Nexiclon Xr Clinical Trials
See Literature
Nexiclon Xr Note
Not Applicable
Nexiclon Xr Patient Counseling
See Literature
