Indapamide

— THERAPEUTIC CATEGORIES —
  • Edema
  • Hypertension

Indapamide Generic Name & Formulations

General Description

Indapamide 1.25mg, 2.5mg; tabs.

Pharmacological Class

Diuretic (indoline).

How Supplied

Contact supplier.

Indapamide Indications

Indications

Edema.

Indapamide Dosage and Administration

Adult

Initially 2.5mg once daily in the AM. After 1 week, may increase to 5mg daily.

Children

Not established.

Indapamide Contraindications

Contraindications

Anuria. Sulfonamide allergy.

Indapamide Boxed Warnings

Not Applicable

Indapamide Warnings/Precautions

Warnings/Precautions

Renal or hepatic impairment. Arrhythmia. Diabetes. Gout. SLE. Postsympathectomy. Excessive fluid loss. Monitor electrolytes, uric acid, glucose, and renal function. K+ supplements or K+-sparing diuretics may be needed. Discontinue if electrolyte disorders develop rapidly. Acute angle-closure glaucoma (with or without acute myopia and choroidal effusions). Elderly. Pregnancy. Nursing mothers: not recommended.

Indapamide Pharmacokinetics

See Literature

Indapamide Interactions

Interactions

Digitalis, lithium toxicity. Adjust antidiabetic medications. NSAIDs may cause renal failure. ACTH, corticosteroids increase hypokalemia risk. May potentiate other antihypertensives. May block epinephrine. May interfere with parathyroid tests.

Indapamide Adverse Reactions

Adverse Reactions

Electrolyte disorders (esp. hypokalemia, hyponatremia), hyperglycemia, hyperuricemia, gout, arrhythmias, headache, nervousness, blurred vision, muscle cramps, dizziness, fatigue, orthostatic hypotension, cough, GI disturbances.

Indapamide Clinical Trials

See Literature

Indapamide Note

Notes

Formerly known under the brand name Lozol.

Indapamide Patient Counseling

See Literature

Indapamide Generic Name & Formulations

General Description

Indapamide 1.25mg, 2.5mg; tabs.

Pharmacological Class

Diuretic (indoline).

How Supplied

Contact supplier.

Indapamide Indications

Indications

Hypertension.

Indapamide Dosage and Administration

Adult

Initially 1.25mg once daily in the AM. May adjust at 4-week intervals to 2.5mg then 5mg once daily.

Children

Not established.

Indapamide Contraindications

Contraindications

Anuria. Sulfonamide allergy.

Indapamide Boxed Warnings

Not Applicable

Indapamide Warnings/Precautions

Warnings/Precautions

Renal or hepatic impairment. Arrhythmia. Diabetes. Gout. SLE. Postsympathectomy. Excessive fluid loss. Monitor electrolytes, uric acid, glucose, and renal function. K+ supplements or K+-sparing diuretics may be needed. Discontinue if electrolyte disorders develop rapidly. Acute angle-closure glaucoma (with or without acute myopia and choroidal effusions). Elderly. Pregnancy. Nursing mothers: not recommended.

Indapamide Pharmacokinetics

See Literature

Indapamide Interactions

Interactions

Digitalis, lithium toxicity. Adjust antidiabetic medications. NSAIDs may cause renal failure. ACTH, corticosteroids increase hypokalemia risk. May potentiate other antihypertensives. May block epinephrine. May interfere with parathyroid tests.

Indapamide Adverse Reactions

Adverse Reactions

Electrolyte disorders (esp. hypokalemia, hyponatremia), hyperglycemia, hyperuricemia, gout, arrhythmias, headache, nervousness, blurred vision, muscle cramps, dizziness, fatigue, orthostatic hypotension, cough, GI disturbances.

Indapamide Clinical Trials

See Literature

Indapamide Note

Notes

Formerly known under the brand name Lozol.

Indapamide Patient Counseling

See Literature