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Hydralazine Tablets Generic Name & Formulations
Legal Class
Rx
General Description
Hydralazine HCl 10mg, 25mg, 50mg, 100mg.
Pharmacological Class
Vasodilator.
See Also
How Supplied
Contact supplier.
Manufacturer
Hydralazine Tablets Indications
Indications
Hypertension.
Hydralazine Tablets Dosage and Administration
Adult
Initially 10mg 4 times daily for 2–4 days, then increase to 25mg 4 times daily for rest of 1st week, then to 50mg 4 times daily; max 300mg/day.
Children
Initially 0.75mg/kg per day in 4 divided doses, increase gradually over 3–4 weeks; max 7.5mg/kg or 200mg daily.
Hydralazine Tablets Contraindications
Contraindications
Coronary artery disease. Mitral valve disease.
Hydralazine Tablets Boxed Warnings
Not Applicable
Hydralazine Tablets Warnings/Precautions
Warnings/Precautions
Suspected coronary artery disease. Cerebrovascular accidents. Aortic aneurysm. Increased intracranial pressure. Renal disease. Treat paresthesias and/or numbness with pyridoxine. Discontinue if blood dyscrasias occur. Obtain CBC and ANA titer periodically; consider discontinuing if SLE occurs. Surgery. Pregnancy (Cat.C). Nursing mothers.
Hydralazine Tablets Pharmacokinetics
See Literature
Hydralazine Tablets Interactions
Interactions
Caution with MAOIs. Profound hypotension with potent parenteral antihypertensives (eg, diazoxide). Antagonized by NSAIDs. May block epinephrine.
Hydralazine Tablets Adverse Reactions
Adverse Reactions
Headache, anorexia, GI disturbances, palpitations, edema, flushing, nasal congestion, lacrimation, rash, tachycardia, angina, orthostatic hypotension, blood dyscrasias, peripheral neuritis, SLE.
Hydralazine Tablets Clinical Trials
See Literature
Hydralazine Tablets Note
Notes
Formerly known under the brand names Apresoline (inj, tabs); Dralzine (tabs).
Hydralazine Tablets Patient Counseling
See Literature
